Biocompatibility of peritoneal dialysis fluid and influence of compositions on peritoneal fibrosis

被引：17
作者：
Higuchi, Chieko [1 ]
Nishimura, Hideki [1 ]
Sanaka, Tsutomu [1 ]
机构：
[1] Tokyo Womens Med Univ, Med Ctr E, Div Internal Med, Arakawa Ku, Tokyo, Japan
来源：
THERAPEUTIC APHERESIS AND DIALYSIS | 2006年 / 10卷 / 04期
关键词：
advanced glycation end-products; glucose degradation products; glucose; lactate; taurine; peritoneal dialysis;
D O I：
10.1111/j.1744-9987.2006.00391.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Conventional peritoneal dialysis fluid (PDF) is a bioincompatible solution because of several components. These unphysiological compositions might contribute to the development of peritoneal fibrosis. In the present overview we summarize the influence of each composition of PDF (acidic pH, high concentration of glucose and glucose degradation products; advanced glycation end-products and lactate) on the peritoneal fibrotic changes in long peritoneal dialysis (PD) patients. We also summarized the report of new approaches to the prevention of peritoneal fibrosis in Japan.
引用
收藏
页码：372 / 379
页数：8
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