Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan

被引:28
作者
Chen, Hsing-Yu [1 ,2 ]
Lin, Yi-Hsuan [1 ,2 ]
Thien, Peck-Foong [3 ]
Chang, Shih-Chieh [4 ,5 ]
Chen, Yu-Chun [3 ,5 ,6 ]
Lo, Su-Shun [5 ]
Yang, Sien-Hung [1 ,7 ]
Chen, Jiun-Liang [1 ,7 ,8 ]
机构
[1] Chang Gung Mem Hosp, Ctr Tradit Chinese Med, Div Chinese Internal Med, Tao Yuan 33378, Taiwan
[2] Chang Gung Univ, Coll Med, Grad Inst Clin Med Sci, Tao Yuan 33302, Taiwan
[3] Natl Yang Ming Univ Hosp, Dept Med Res & Educ, Ilan 26042, Taiwan
[4] Natl Yang Ming Univ Hosp, Dept Internal Med, Div Chest Med, Ilan 26042, Taiwan
[5] Natl Yang Ming Univ, Sch Med, Fac Med, Taipei 112, Taiwan
[6] Natl Yang Ming Univ, Sch Med, Inst Hosp & Hlth Care Adm, Taipei 112, Taiwan
[7] Chang Gung Univ, Coll Med, Sch Tradit Chinese Med, Tao Yuan 33302, Taiwan
[8] Natl Yang Ming Univ, Sch Med, Inst Tradit Med, Taipei 112, Taiwan
关键词
QING-LONG-TANG; AIRWAY INFLAMMATION; ALLERGIC RHINITIS; PHARMACOLOGICAL-PROPERTIES; TRADITIONAL MEDICINES; ANTIALLERGIC ACTIVITY; ALTERNATIVE MEDICINE; CHILDHOOD ASTHMA; MURINE MODEL; IN-VIVO;
D O I
10.1155/2013/125943
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Asthma is one of the most common allergic respiratory diseases around the world and places great burden on medical payment. Chinese herbal medicine (CHM) is commonly used for Taiwanese children to control diseases. The aim of this study is to analyze the CHM prescriptions for asthmatic children by using a nationwide clinical database. The National Health Insurance Research Database (NHIRD) was used to perform this study. Medical records from 1997 to 2009 with diagnosis with asthma made for children aged 6 to 18 were included into the analysis. Association rule mining and social network analysis were used to analyze the prevalence of single CHM and its combinations. Ma-Xing-Gan-Shi-Tang (MXGST) was the most commonly used herbal formula (HF) (20.2% of all prescriptions), followed by Xiao-Qing-Long-Tang (13.1%) and Xing-Su-San (12.8%). Zhe Bei Mu is the most frequently used single herb (SH) (14.6%), followed by Xing Ren (10.7%). MXGST was commonly used with Zhe Bei Mu (3.5%) and other single herbs capable of dispelling phlegm. Besides, MXGST was the core formula to relieve asthma. Further studies about efficacy and drug safety are needed for the CHM commonly used for asthma based on the result of this study.
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页数:10
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