Clinical activity of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC) and a BRCA mutation (BRCAmut): Analysis of pooled data from Study 10 (parts 1, 2a, and 3) and ARIEL2 (parts 1 and 2)

被引：8

作者：

Kristeleit, R. S. ^{[1
]}

Shapira-Frommer, R. ^{[2
]}

Oaknin, A. ^{[3
]}

Balmana, J. ^{[3
]}

Ray-Coquard, I. L. ^{[4
,5
]}

Domchek, S. ^{[6
]}

Tinker, A. V. ^{[7
]}

Castro, C. M. ^{[8
]}

Welch, S. ^{[9
]}

Poveda, A. M. ^{[10
]}

Bell-Mcguinn, K. ^{[11
]}

Konecny, G. ^{[12
]}

Giordano, H. ^{[13
]}

Maloney, L. ^{[13
]}

Goble, S. ^{[14
]}

Rolfe, L. ^{[15
]}

Oza, A. ^{[16
]}

机构：

[1] UCL, Inst Canc, Oncol, London, England

[2] Sheba Med Ctr, Med Oncol, Ramat Gan, Israel

[3] Vall dHebron Univ Hosp, Vall dHebron Inst Oncol, Med Oncol, Barcelona, Spain

[4] Ctr Leon Berard, GINECO, Oncol, Lyon, France

[5] Univ Claude Bernard, Lyon, France

[6] Univ Penn, Med Oncol, Philadelphia, PA 19104 USA

[7] British Columbia Canc Agcy, Med, Vancouver, BC, Canada

[8] Harvard Med Sch, Massachusetts Gen Hosp, Med, Gynecol Oncol, Boston, MA USA

[9] London Reg Canc Program, Div Med Oncol, London, ON, Canada

[10] Valencian Inst Oncol, Gynecol, Clin Area Gynecol Oncol, Valencia, Spain

[11] Mem Sloan Kettering Canc Ctr, Gynecol Med Oncol, 1275 York Ave, New York, NY 10021 USA

[12] Univ Calif Los Angeles, Med Hematol & Oncol, Los Angeles, CA USA

[13] Clovis Oncol Inc, Clin Sci, Boulder, CO USA

[14] Clovis Oncol Inc, Biostat, Boulder, CO USA

[15] Clovis Oncol Inc, Clin & Preclin Dev, Boulder, CO USA

[16] Univ Hlth Network, Princess Margaret Canc Ctr, Med Oncol, Toronto, ON, Canada

来源：

ANNALS OF ONCOLOGY | 2016年 / 27卷

关键词：

D O I：

10.1093/annonc/mdw374.3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

856O

引用

页数：1