Corrosion resistance and drug release profile of gentamicin-loaded polyelectrolyte multilayers on magnesium alloys: Effects of heat treatment

被引：51

作者：

Zhao, Yanbin ^{[1
]}

Chen, Xueyang ^{[1
]}

Li, Shuoqi ^{[1
]}

Zeng, Rongchang ^{[1
]}

Zhang, Fen ^{[1
]}

Wang, Zhenlin ^{[2
]}

Guan, Shaokang ^{[3
]}

机构：

[1] Shandong Univ Sci & Technol, Coll Mat Sci & Engn, Qingdao 266590, Shandong, Peoples R China

[2] Chongqing Univ Technol, Coll Mat Sci & Engn, Chongqing 400065, Peoples R China

[3] Zhengzhou Univ, Sch Mat Sci & Engn, Zhengzhou 450001, Henan, Peoples R China

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2019年 / 547卷

基金：

中国国家自然科学基金;

关键词：

Magnesium alloy; Layer-by-layer; Heat treatment; Corrosion resistance; Antibacterial property; Sustained release; IN-VITRO CORROSION; ANTIBACTERIAL PROPERTIES; BIOFILM FORMATION; COATINGS; SURFACE; FILMS; POLYSILOXANE; BEHAVIOR;

D O I：

10.1016/j.jcis.2019.04.017

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Magnesium (Mg) alloys have received considerable attentions as the emerging biodegradable implant materials in orthopedic surgery applications. However, the rapid corrosion rate and the susceptibility to bacterial infection have prevented their wide spread applications to date. In this work, the gentamicin-loaded multilayers have been constructed on Mg alloys through spin-assisted layer-by-layer (SLbL) assembly. Heat treatment is applied for improving the corrosion resistance and prolonging the drug release profile. In addition, the treated multilayer can promote the formation of hydroxyapatite (HA) during the long-time immersion in Hank's balanced salt solution (HBSS). (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：309 / 317

页数：9

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