Large-Scale, Ultrapliable, and Free-Standing Nanomembranes

被引：52
|
作者：
Kang, Edward [1 ,3 ]
Ryoo, Jihee [1 ,4 ]
Jeong, Gi Seok [1 ]
Choi, Yoon Young [1 ]
Jeong, Seung Min [1 ]
Ju, Jongil [1 ]
Chung, Seok [5 ]
Takayama, Shuichi [6 ,7 ]
Lee, Sang-Hoon [1 ,2 ]
机构：
[1] Korea Univ, Coll Hlth Sci, Dept Biomed Engn, Seoul 136703, South Korea
[2] Korea Univ, KU KIST Grad Sch Converging Sci & Technol, Seoul 136713, South Korea
[3] Korea Univ, Dept Biomicrosyst Technol, Seoul 136713, South Korea
[4] Coway Co, Cosmet R&D Ctr, Seoul 153792, South Korea
[5] Korea Univ, Sch Mech Engn, Seoul 136713, South Korea
[6] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA
[7] UNIST, Div Nanobio & Chem Engn, WCU Project, Ulsan 689798, South Korea
来源：
ADVANCED MATERIALS | 2013年 / 25卷 / 15期
基金：
新加坡国家研究基金会;
关键词：
ultrathin PDMS membrane; large-scale elastic nanomembrane; epithelial monolayer's modulus; BASEMENT-MEMBRANES; CELL; FABRICATION; RECOVERY;
D O I：
10.1002/adma.201204619
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The creation and characterization of large-area ultrathin highly pliable free-standing PDMS membranes and their application to the study of cellular epithelia is described. The ultra-thin membranes permitted the straight forward calculation of cell monolayer moduli, derived from measured stress-strain curves. These measurements allowed the unprecedented detection of cellular-level injury in the epithelia caused by the rupture of cell-cell tight junctions in response to stretching. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2167 / 2173
页数：7
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