Large-Scale, Ultrapliable, and Free-Standing Nanomembranes

被引：52

作者：

Kang, Edward ^{[1
,3
]}

Ryoo, Jihee ^{[1
,4
]}

Jeong, Gi Seok ^{[1
]}

Choi, Yoon Young ^{[1
]}

Jeong, Seung Min ^{[1
]}

Ju, Jongil ^{[1
]}

Chung, Seok ^{[5
]}

Takayama, Shuichi ^{[6
,7
]}

Lee, Sang-Hoon ^{[1
,2
]}

机构：

[1] Korea Univ, Coll Hlth Sci, Dept Biomed Engn, Seoul 136703, South Korea

[2] Korea Univ, KU KIST Grad Sch Converging Sci & Technol, Seoul 136713, South Korea

[3] Korea Univ, Dept Biomicrosyst Technol, Seoul 136713, South Korea

[4] Coway Co, Cosmet R&D Ctr, Seoul 153792, South Korea

[5] Korea Univ, Sch Mech Engn, Seoul 136713, South Korea

[6] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA

[7] UNIST, Div Nanobio & Chem Engn, WCU Project, Ulsan 689798, South Korea

来源：

ADVANCED MATERIALS | 2013年 / 25卷 / 15期

基金：

新加坡国家研究基金会;

关键词：

ultrathin PDMS membrane; large-scale elastic nanomembrane; epithelial monolayer's modulus; BASEMENT-MEMBRANES; CELL; FABRICATION; RECOVERY;

D O I：

10.1002/adma.201204619

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The creation and characterization of large-area ultrathin highly pliable free-standing PDMS membranes and their application to the study of cellular epithelia is described. The ultra-thin membranes permitted the straight forward calculation of cell monolayer moduli, derived from measured stress-strain curves. These measurements allowed the unprecedented detection of cellular-level injury in the epithelia caused by the rupture of cell-cell tight junctions in response to stretching. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2167 / 2173

页数：7

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