Instrumentation for the measurement of electric brain responses to transcranial magnetic stimulation

被引：187

作者：

Virtanen, J

Ruohonen, J

Näätänen, R

Ilmoniemi, RJ

机构：

[1] Univ Helsinki, Dept Psychol, Cognit Brain Res Unit, SF-00100 Helsinki, Finland

[2] Univ Helsinki, Cent Hosp, Med Engn Ctr, Biomag Lab, Helsinki, Finland

[3] Univ Helsinki, Cent Hosp, Dept Radiol, Helsinki, Finland

来源：

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING | 1999年 / 37卷 / 03期

基金：

芬兰科学院;

关键词：

electroencephalography (EEG); transcranial magnetic stimulation (TMS); artefact; amplifier;

D O I：

10.1007/BF02513307

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

There is described a 60-channel EEG acquisition system designed for the recording of scalp-potential distributions starting just 2.5 ms after individual transcranial magnetic stimulation (TMS) pulses, The amplifier comprises gain-control and sample-and-hold circuits to prevent large artefacts from magnetically induced voltages in the leads. The maximum amplitude of the stimulus artefact during the 2.5 ms gating period is 1.7 mu V, and 5 ms after the TMS pulse it is only 0.9 mu V. It is also shown that mechanical forces to the electrodes under the stimulator coil are a potential source of artefacts, even though, with chlorided silver wire and Ag/AgCl-pellet electrodes, the artefact is smaller than 1 mu V. The TMS-compatible multichannel EEG system makes it possible to locate TMS-evoked electric activity in the brain.

引用

页码：322 / 326

页数：5