Synthesis and biological evaluation of 4-alkoxy substituted trinems .1.

被引：11
作者：
Andreotti, D
Biondi, S
DiFabio, R
Donati, D
Piga, E
Rossi, T
机构：
[1] Glaxo Wellcome S.p.A., Medicines Research Centre, 37138 Verona
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 16期
关键词：
D O I：
10.1016/0960-894X(96)00359-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Synthesis of new 4-alkoxy substituted trinems 4, 5, 6, 7 and 8 together with their antibacterial profiles compared to imipenem and GV104326 (2) are described. The good antibacterial profile observed for derivatives 4-7 encouraged further exploration of these derivatives. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码：2019 / 2024
页数：6
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