Spatiotemporal pattern of the postnatal astrogliogenesis in the rat hippocampal formation

被引:6
作者
Setkowicz, Z [1 ]
Pawlinski, R [1 ]
Ziaja, M [1 ]
Janeczko, K [1 ]
机构
[1] Jagiellonian Univ, Inst Zool, Dept Neuroanat, PL-30060 Krakow, Poland
关键词
astrocyte proliferation; 3H-thymidine autoradiography; S-100 beta protein immunocytochemistry; hippocampus; dentate gyrus; Ammon's horn; rat;
D O I
10.1016/S0736-5748(99)00014-3
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Newborn, 2-, 4-, 8-, 16- and 30-day-old Wistar rats were injected with 3H-thymidine and sacrificed following 4 h. survival time. Brain sections containing the dorsal part of hippocampal formation were immunostained for S-100 beta protein and subjected to autoradiography to visualize proliferating astrocytes. Microscopical observations revealed age-dependent changes in the number and distribution of proliferating astrocytes. The changes were considered as being related to the neurogenetic gradient characteristic to the hippocampal formation. (C) 1999 ISDN. Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:215 / 224
页数:10
相关论文
共 29 条
[1]   MIGRATION AND DISTRIBUTION OF 2 POPULATIONS OF HIPPOCAMPAL GRANULE CELL PRECURSORS DURING THE PERINATAL AND POSTNATAL PERIODS [J].
ALTMAN, J ;
BAYER, SA .
JOURNAL OF COMPARATIVE NEUROLOGY, 1990, 301 (03) :365-381
[2]   MOSAIC ORGANIZATION OF THE HIPPOCAMPAL NEUROEPITHELIUM AND THE MULTIPLE GERMINAL SOURCES OF DENTATE GRANULE CELLS [J].
ALTMAN, J ;
BAYER, SA .
JOURNAL OF COMPARATIVE NEUROLOGY, 1990, 301 (03) :325-342
[3]  
BAYER SA, 1993, NEUROTOXICOLOGY, V14, P83
[5]   DIFFERENTIATION OF NEWLY BORN NEURONS AND GLIA IN THE DENTATE GYRUS OF THE ADULT-RAT [J].
CAMERON, HA ;
WOOLLEY, CS ;
MCEWEN, BS ;
GOULD, E .
NEUROSCIENCE, 1993, 56 (02) :337-344
[6]  
GASSER UE, 1990, J NEUROSCI, V10, P1276
[7]   NEURONAL REGULATION OF ASTROGLIAL MORPHOLOGY AND PROLIFERATION INVITRO [J].
HATTEN, ME .
JOURNAL OF CELL BIOLOGY, 1985, 100 (02) :384-396
[8]   NEURONAL INHIBITION OF ASTROGLIAL CELL-PROLIFERATION IS MEMBRANE MEDIATED [J].
HATTEN, ME .
JOURNAL OF CELL BIOLOGY, 1987, 104 (05) :1353-1360
[9]   TRANSFORMING GROWTH FACTOR-BETA-S INHIBIT MITOGEN-STIMULATED PROLIFERATION OF ASTROCYTES [J].
HUNTER, KE ;
SPORN, MB ;
DAVIES, AM .
GLIA, 1993, 7 (03) :203-211
[10]  
Jacobson M, 1991, DEV NEUROBIOLOGY, P3