Determining the Role of Cystectomy for High-grade T1 Urothelial Carcinoma

被引:19
作者
Daneshmand, Siamak
机构
[1] USC Institute of Urology, Norris Comprehensive Cancer Center, Los Angeles, CA 90089, 1441 Eastlake Avenue
关键词
TRANSITIONAL-CELL-CARCINOMA; BACILLUS-CALMETTE-GUERIN; SUPERFICIAL BLADDER-CANCER; 2ND TRANSURETHRAL RESECTION; TERM-FOLLOW-UP; STAGE T1; RADICAL CYSTECTOMY; TUMOR PROGRESSION; PROGNOSTIC-SIGNIFICANCE; IN-SITU;
D O I
10.1016/j.ucl.2013.01.003
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
High-grade T1 (HGT1) urothelial carcinoma is an invasive disease with high predisposition for recurrence and progression. The optimal treatment of HGT1 disease remains controversial. Clinical HGT1 disease represents a heterogeneous group of patients with variable clinical behavior. Radical cystectomy for HGT1 disease is associated with excellent survival and offers the best opportunity for cure; however, it has a potential cost of decrease in quality of life. This article summarizes features associated with increased risk of progression and provides a framework for optimal treatment strategy with a focus on the role of radical cystectomy for HGT1 disease.
引用
收藏
页码:233 / +
页数:16
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