Dietary and lifestyle guidelines for the prevention of Alzheimer's disease

被引：236

作者：

Barnard, Neal D. ^{[1
,2
]}

Bush, Ashley I. ^{[3
]}

Ceccarelli, Antonia ^{[4
]}

Cooper, James ^{[1
]}

de Jager, Celeste A. ^{[5
]}

Erickson, Kirk I. ^{[6
]}

Fraser, Gary ^{[7
]}

Kesler, Shelli ^{[8
]}

Levin, Susan M. ^{[2
]}

Lucey, Brendan ^{[9
]}

Morris, Martha Clare ^{[10
]}

Squitti, Rosanna ^{[11
,12
]}

机构：

[1] George Washington Univ, Sch Med, Dept Med, Washington, DC 20016 USA

[2] Phys Comm Responsible Med, Washington, DC USA

[3] Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Melbourne, Vic, Australia

[4] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Neurol,Lab Neuroimaging Res,Partners MS Ctr, Boston, MA 02115 USA

[5] Univ Oxford, Nuffield Dept Clin Med, OPTIMA, Oxford, England

[6] Univ Pittsburgh, Dept Psychol, Pittsburgh, PA 15260 USA

[7] Loma Linda Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Loma Linda, CA 92350 USA

[8] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

[9] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA

[10] Rush Univ, Dept Internal Med, Sect Nutr & Nutr Epidemiol, Chicago, IL 60612 USA

[11] AFaR Fatebenefratelli Hosp San Giovanni Calibita, Dept Neurosci, Rome, Italy

[12] Ist Ricovero & Cura Carattere Sci IRCCS San Raffa, Lab Neurodegenerat, Rome, Italy

来源：

NEUROBIOLOGY OF AGING | 2014年 / 35卷

关键词：

Dementia; Alzheimer's disease; Prevention; Nutrition; Saturated fat; Trans fatty acids; Vitamin E; Iron; Copper; Exercise; MILD COGNITIVE IMPAIRMENT; FAT INTAKE; RISK; DECLINE; MIDLIFE; DEMENTIA; CHOLESTEROL; POPULATION; ALUMINUM; RESERVE;

D O I：

10.1016/j.neurobiolaging.2014.03.033

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Risk of developing Alzheimer's disease is increased by older age, genetic factors, and several medical risk factors. Studies have also suggested that dietary and lifestyle factors may influence risk, raising the possibility that preventive strategies may be effective. This body of research is incomplete. However, because the most scientifically supported lifestyle factors for Alzheimer's disease are known factors for cardiovascular diseases and diabetes, it is reasonable to provide preliminary guidance to help individuals who wish to reduce their risk. At the International Conference on Nutrition and the Brain, Washington, DC, July 19-20, 2013, speakers were asked to comment on possible guidelines for Alzheimer's disease prevention, with an aim of developing a set of practical, albeit preliminary, steps to be recommended to members of the public. From this discussion, 7 guidelines emerged related to healthful diet and exercise habits. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：S74 / S78

页数：5

共 55 条

[1]

Barnard N.D., 2014, NEUROBIOL A IN PRESS

[2] Midlife predictors of Alzheimer's disease [J].

Bendlin, B. B. ;

Carlsson, C. M. ;

Gleason, C. E. ;

Johnson, S. C. ;

Sodhi, A. ;

Gallagher, C. L. ;

Puglielli, L. ;

Engelman, C. D. ;

Ries, M. L. ;

Xu, G. ;

Wharton, W. ;

Asthana, S. .

MATURITAS, 2010, 65 (02) :131-137

[3]

Beydoun MA, 2007, AM J CLIN NUTR, V85, P1103

[4] Association of Sleep Characteristics and Cognition in Older Community-Dwelling Men: the MrOS Sleep Study [J].

Blackwell, Terri ;

Yaffe, Kristine ;

Ancoli-Israel, Sonia ;

Redline, Susan ;

Ensrud, Kristine E. ;

Stefanick, Marcia L. ;

Laffan, Alison ;

Stone, Katie L. .

SLEEP, 2011, 34 (10) :1347-1356

[5] Evidence-based criteria in the nutritional context [J].

Blumberg, Jeffrey ;

Heaney, Robert P. ;

Huncharek, Michael ;

Scholl, Theresa ;

Stampfer, Meir ;

Vieth, Reinhold ;

Weaver, Connie M. ;

Zeisel, Steven H. .

NUTRITION REVIEWS, 2010, 68 (08) :478-484

[6] The Risks of Copper Toxicity Contributing to Cognitive Decline in the Aging Population and to Alzheimer's Disease [J].

Brewer, George J. .

JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION, 2009, 28 (03) :238-242

[7] ALUMINUM, NEUROFIBRILLARY DEGENERATION AND ALZHEIMERS DISEASE [J].

CRAPPER, DR ;

KRISHNAN, SS ;

QUITTKAT, S .

BRAIN, 1976, 99 (MAR) :67-80

[8] BRAIN ALUMINUM DISTRIBUTION IN ALZHEIMERS DISEASE AND EXPERIMENTAL NEUROFIBRILLARY DEGENERATION [J].

CRAPPER, DR ;

KRISHNAN, SS ;

DALTON, AJ .

SCIENCE, 1973, 180 (4085) :511-513

[9] Training your brain: Do mental and physical (MAP) training enhance cognition through the process of neurogenesis in the hippocampus? [J].

Curlik, D. M., II ;

Shors, T. J. .

NEUROPHARMACOLOGY, 2013, 64 :506-514

[10] Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial [J].

de Jager, Celeste A. ;

Oulhaj, Abderrahim ;

Jacoby, Robin ;

Refsum, Helga ;

Smith, A. David .

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2012, 27 (06) :592-600

← 1 2 3 4 5 6 →