Batch injection analysis with amperometric detection: application for simultaneous analysis using a single working electrode

In this work, we describe for the first time the association of batch injection analysis (BIA) with dual pulse amperometric (DPA) detection for simultaneous determination of multi-analytes using a single working electrode. The sequence of pulses is selected in such a way that the analytes are detected individually and independently at the same working unmodified electrode (using a correction factor). BIA provides fast response (high-throughput analysis), elevated precision, reduction of sample volumes and minimization of waste. To illustrate the potential of this method, BIA-DPA was applied for the simultaneous determination of biodiesel preservatives (tert-butylhydroquinone and butylated hydroxyanisole) and pharmaceutical compounds (paracetamol and caffeine or dipyrone and caffeine).