Ho(a)xing Autophagy to Regulate Development

被引:3
作者
Campello, Silvia [1 ]
Cecconi, Francesco [1 ,2 ,3 ]
机构
[1] IRCCS Fdn Santa Lucia, I-00143 Rome, Italy
[2] Danish Canc Soc Res Ctr, Unit Cell Stress & Survival, DK-2100 Copenhagen, Denmark
[3] Univ Roma Tor Vergata, Dept Biol, I-00133 Rome, Italy
关键词
MAMMALIAN DEVELOPMENT; CELL-DEATH;
D O I
10.1016/j.devcel.2013.12.018
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In this issue of Developmental Cell, Banreti et al. (2014) demonstrate that canonical autophagy is inhibited in the Drosophila fat body by Hox transcriptional factors. This regulation involves repression of the Atg genes. Programmed developmental autophagy is thus under Hox control and may influence cell fate determination.
引用
收藏
页码:3 / 4
页数:2
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