Refractory Otitis Media: An Unusual Presentation of Childhood Granulomatosis With Polyangiitis

被引：2

作者：

Uppal, Preena ^{[1
,2
]}

Taitz, Jonny ^{[1
,2
]}

Wainstein, Brynn ^{[2
,3
]}

Soma, Marlene ^{[2
,4
]}

Belessis, Yvonne ^{[2
,5
]}

Gray, Paul ^{[2
,3
]}

机构：

[1] Sydney Childrens Hosp Network, Dept Gen Pediat, Randwick, NSW, Australia

[2] Univ New S Wales, Sch Womens & Childrens Hlth, Sydney, NSW 2052, Australia

[3] Sydney Childrens Hosp Network, Dept Immunol, Randwick, NSW, Australia

[4] Sydney Childrens Hosp Network, Dept Ear Nose & Throat Surg, Randwick, NSW, Australia

[5] Sydney Childrens Hosp Network, Dept Resp Med, Randwick, NSW, Australia

来源：

PEDIATRIC PULMONOLOGY | 2014年 / 49卷 / 03期

关键词：

Wegener's granulomatosis; chronic otitis media; hearing loss; atypical pneumonia; childhood vasculitis; ANCA-ASSOCIATED VASCULITIS; HENOCH-SCHONLEIN PURPURA; WEGENERS-GRANULOMATOSIS; CHILDREN; YOUNG;

D O I：

10.1002/ppul.22746

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Childhood granulomatosis with polyangiitis (cGPA), previously known as Wegener's granulomatosis, is a rare, potentially fatal necrotizing vasculitis, the symptoms of which overlap with infection. We present a 16-year-old girl who, following 6 months of treatment for persistent middle ear effusion with progressive sensorineural hearing loss, developed rapidly progressing pneumonia, with pleural effusion, and multiple cavitatory lung lesions. Investigations demonstrated high titer c-ANCA and nasal septal biopsy confirmed the diagnosis of cGPA. This case highlights the difficulty in diagnosing cGPA and the potentially life-threatening consequences of failing to do so. Pediatr Pulmonol. 2014; 49:E21-E24. (c) 2013 Wiley Periodicals, Inc.

引用

页码：E21 / E24

页数：4

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