A radical cyclization strategy for the concise total synthesis of (+/-)-geissoschizine

被引：43
|
作者：
Takayama, H
Watanabe, F
Kitajima, M
Aimi, N
机构：
[1] Faculty of Pharmaceutical Sciences, Chiba University, Chiba, 263, 1-33, Yayoi-cho, Inage-ku
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 30期
关键词：
D O I：
10.1016/S0040-4039(97)01186-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A short synthetic route to (+/-)-geissoschizine (1) was developed that features the construction of a Corynanthe-skeleton via radical cyclization of vinyl iodide, which was easily prepared by assembly of three fragments. New pentacyclic molecules formed by the radical cyclization were also reported. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：5307 / 5310
页数：4
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