Change Point Estimation of the Hippocampal Volumes in Alzheimer's Disease

被引：0

作者：

Tang, Xiaoying ^{[1
]}

Albert, Marilyn ^{[2
,3
]}

Miller, Michael I. ^{[2
,3
]}

Younes, Laurent ^{[2
,3
]}

机构：

[1] Sun Yat Sen Univ, CMU Joint Inst Engn, Guangzhou, Guangdong, Peoples R China

[2] Johns Hopkins Univ, Dept Neurol, Baltimore, MD USA

[3] Johns Hopkins Univ, Ctr Imaging Sci, Baltimore, MD USA

来源：

2016 13TH CONFERENCE ON COMPUTER AND ROBOT VISION (CRV) | 2016年

基金：

美国国家卫生研究院; 美国国家科学基金会; 中国国家自然科学基金;

关键词：

change point; maximum likelihood estimation; linear mixed-effects; Alzheimer's disease; hippocampus; MILD COGNITIVE IMPAIRMENT; DIFFEOMORPHOMETRY; AMYGDALA; ATROPHY;

D O I：

10.1109/CRV.2016.13

中图分类号：

TP24 [机器人技术];

学科分类号：

080202 ; 1405 ;

摘要：

Volumetric changes in the hippocampus have been shown to precede clinical symptom onset during the preclinical phase of Alzheimer's disease (AD). In this paper, we propose a novel statistical method for estimating the change point of the hippocampus, as extracted from structural magnetic resonance imaging scans, in relation to clinical symptom onset. We used a linear mixed-effect statistical model. Maximum likelihood estimation was employed as the strategy that was applied in two phases.

引用

页码：358 / 361

页数：4

共 50 条

[41] Volumetric changes within hippocampal subfields in Alzheimer's disease continuum [J].

Hari, Emre ;

Kurt, Elif ;

Bayram, Ali ;

Kizilates-Evin, Gozde ;

Acar, Burak ;

Demiralp, Tamer ;

Gurvit, Hakan .

NEUROLOGICAL SCIENCES, 2022, 43 (07) :4175-4183

[42] Insensitivity of visual assessment of hippocampal atrophy in familial Alzheimer's disease [J].

Ringman, John Matthew ;

Pope, Whitney ;

Salamon, Noriko .

JOURNAL OF NEUROLOGY, 2010, 257 (05) :839-842

[43] BIOMARKER CHANGE-POINT ESTIMATION WITH RIGHT CENSORING IN LONGITUDINAL STUDIES [J].

Tang, Xiaoying ;

Miller, Michael I. ;

Younes, Laurent .

ANNALS OF APPLIED STATISTICS, 2017, 11 (03) :1738-1762

[44] Study on dynamic characteristics' change of hippocampal neuron reduced models caused by the Alzheimer's disease [J].

Peng, Yueping ;

Wang, Jue ;

Zheng, Chongxun .

JOURNAL OF BIOLOGICAL DYNAMICS, 2016, 10 (01) :250-262

[45] Mapping hippocampal and ventricular change in Alzheimer disease [J].

Thompson, PM ;

Hayashi, KM ;

de Zubicaray, GI ;

Janke, AL ;

Rose, SE ;

Semple, J ;

Hong, MS ;

Herman, DH ;

Gravano, D ;

Doddrell, DM ;

Toga, AW .

NEUROIMAGE, 2004, 22 (04) :1754-1766

[46] The Value of Hippocampal and Temporal Horn Volumes and Rates of Change in Predicting Future Conversion to AD [J].

Macdonald, Kate E. ;

Bartlett, Jonathan W. ;

Leung, Kelvin K. ;

Ourselin, Sebastien ;

Barnes, Josephine .

ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 2013, 27 (02) :168-173

[47] Correlation between hippocampal subfields volumes and cerebrospinal fluid biomarkers in patients with Alzheimer's disease [J].

Zhu Zhengyang ;

Gong Chengbing ;

Qin Ruomeng ;

Song Wenting ;

Zhao Hui ;

Xu Yun .

CEREBROVASCULAR DISEASES, 2023, 52 :135-135

[48] Prospective memory in prodromal Alzheimer's disease: Real world relevance and correlations with cortical thickness and hippocampal subfield volumes [J].

Nurdal, Volkan ;

Wearn, Alfie ;

Knight, Michael ;

Kauppinen, Risto ;

Coulthard, Elizabeth .

NEUROIMAGE-CLINICAL, 2020, 26

[49] Associations between hippocampal morphometry and neuropathologic markers of Alzheimer's disease using 7 T MRI [J].

Blanken, Anna E. ;

Hurtz, Sona ;

Zarow, Chris ;

Biado, Kristina ;

Honarpisheh, Hedieh ;

Somme, Johanne ;

Brook, Jenny ;

Tung, Spencer ;

Kraft, Emily ;

Lo, Darrick ;

Ng, Denise W. ;

Vinters, Harry V. ;

Apostolova, Liana G. .

NEUROIMAGE-CLINICAL, 2017, 15 :56-61

[50] 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease [J].

Apostolova, Liana G. ;

Dinov, Ivo D. ;

Dutton, Rebecca A. ;

Hayashi, Kiralee M. ;

Toga, Arthur W. ;

Cummings, Jeffrey L. ;

Thompson, Paul M. .

BRAIN, 2006, 129 :2867-2873

← 1 2 3 4 5 →