Did free drugs for smoking cessation effect treatment success?

被引:0
作者
Arslan, Sertac [1 ]
机构
[1] Hitit Univ, Dept Pulm Med, Med Fac, Corum, Turkey
关键词
Smoking cessation; Varenicline; Bupropion; CLINICAL-PRACTICE GUIDELINE; TREATING TOBACCO USE; RECEPTOR PARTIAL AGONIST; SUSTAINED-RELEASE BUPROPION; 2008; UPDATE; VARENICLINE; DEPENDENCE; PLACEBO; ADULTS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background and Aim: Drugs used for smoking cessation had not been paid by health insurance system in our country; however, these drugs started to be given freely by community health services in case an authorized doctor prescribe them. We evaluate the treatment success after smoking cessation drugs become free. Methods: Eighty-five patients (48 males, 37 females) admitted to smoking cessation clinic at a university in Corum between July 1st 2015 - December 31st 2015 were evaluated retrospectively. Results: Mean age of patients was 37.9 years. Most common symptoms were exercise dyspnea (71.8%) and productive cough (61.2%). Sixty-six patients were prescribed Vareniclin (77.6%) and bupropion prescribed 19 patients (22.4%). At the end of 3 months therapy 26 patients (30.6%) quit smoking. Percentage of smoking cessation was 33.3% for males and 27% for females; moreover, 33.3% for varenicline and 21.1% for bupropion group (p=0.309). Mean duration of smoking was 22.1 years for quitters and 16.5 years for non-quitters (p=0.068). Fagerstrom smoking scale was adapted to the study as low (0-4), moderate (5-7), high (8-10) nicotine dependence. Percentage of quitters was 20.8%, 30.4% and 36.8% for low, moderate and high dependence patients respectively (p=0.411). There was no significant difference between varenicline and bupropion for treatment success according to nicotine dependence levels. For the patients who quit smoking, pre-treatment and post-treatment spirometry tests were compared. Mean PEF% were increased from 71.6% to 77.7% (p=0.062), mean MEF75% were increased from 75.2% to 81.2% (p=0.075). Conclusion: Free drugs for smoking cessation treatment may decrease treatment success.
引用
收藏
页码:217 / 220
页数:4
相关论文
共 21 条
[1]  
Agarwal SK, 2017, MED SCI, V21, P60
[2]  
Agarwal SK, 2017, MED SCI, V21, P91
[3]   Treating tobacco use and dependence - An evidence-based clinical practice guideline for tobacco cessation [J].
Anderson, JE ;
Jorenby, DE ;
Scott, WJ ;
Fiore, MC .
CHEST, 2002, 121 (03) :932-941
[4]   Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial [J].
Anthenelli, Robert M. ;
Benowitz, Neal L. ;
West, Robert ;
St Aubin, Lisa ;
McRae, Thomas ;
Lawrence, David ;
Ascher, John ;
Russ, Cristina ;
Krishen, Alok ;
Evins, A. Eden .
LANCET, 2016, 387 (10037) :2507-2520
[5]  
Arguder E, 2013, FACTORS AFFECTING SU
[6]   Effects of Nicotine Patch vs Varenicline vs Combination Nicotine Replacement Therapy on Smoking Cessation at 26 Weeks A Randomized Clinical Trial [J].
Baker, Timothy B. ;
Piper, Megan E. ;
Stein, James H. ;
Smith, Stevens S. ;
Bolt, Daniel M. ;
Fraser, David L. ;
Fiore, Michael C. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2016, 315 (04) :371-379
[7]   Nicotine receptor partial agonists for smoking cessation [J].
Cahill, Kate ;
Lindson-Hawley, Nicola ;
Thomas, Kyla H. ;
Fanshawe, Thomas R. ;
Lancaster, Tim .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2016, (05)
[8]  
Cahill K, 2013, COCHRANE DB SYST REV, DOI [10.1002/14651858.CD009329.pub2, 10.1002/14651858.CD006103.pub6]
[9]  
Fiore MC, 2000, JAMA-J AM MED ASSOC, V283, P3244
[10]  
Fiore MC, 2008, RESP CARE, V53, P1217