Synthetic chloride transporters with the binding mode observed in a ClC chloride channel

被引：22

作者：

Choi, Ye Rin ^{[2
]}

Chae, Min Kyung ^{[2
]}

Kim, Dongwook ^{[1
]}

Lah, Myoung Soo ^{[1
]}

Jeong, Kyu-Sung ^{[2
]}

机构：

[1] Ulsan Natl Inst Sci & Technol, Interdisciplinary Sch Green Energy, Ulsan 689798, South Korea

[2] Yonsei Univ, Dept Chem, Seoul 120749, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 83期

基金：

新加坡国家研究基金会;

关键词：

MEMBRANE TRANSPORTERS; ANION TRANSPORT; BICARBONATE; RECEPTORS;

D O I：

10.1039/c2cc35743g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of synthetic molecules bearing the same hydrogen bonding mode observed in StClC were prepared and their transport ability of chloride ion across a lipid membrane was systematically optimized.

引用

页码：10346 / 10348

页数：3

共 57 条

[1] Structurally simple lipid bilayer transport agents for chloride and bicarbonate [J].

Andrews, Natalie J. ;

Haynes, Cally J. E. ;

Light, Mark E. ;

Moore, Stephen J. ;

Tong, Christine C. ;

Davis, Jeffery T. ;

Harrell, William A., Jr. ;

Gale, Philip A. .

CHEMICAL SCIENCE, 2011, 2 (02) :256-260

[2] Monoacylglycerols as transmembrane Cl- anion transporters [J].

Bahmanjah, Soheila ;

Zhang, Ning ;

Davis, Jeffery T. .

CHEMICAL COMMUNICATIONS, 2012, 48 (37) :4432-4434

[3] Catechols as Membrane Anion Transporters [J].

Berezin, Sofya Kostina ;

Davis, Jeffery T. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (07) :2458-+

[4] Synthetic membrane transporters [J].

Boon, JM ;

Smith, BD .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (06) :749-756

[5] Squaramides as Potent Transmembrane Anion Transporters [J].

Busschaert, Nathalie ;

Kirby, Isabelle L. ;

Young, Sarah ;

Coles, Simon J. ;

Horton, Peter N. ;

Light, Mark E. ;

Gale, Philip A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (18) :4426-4430

[6] Structure-Activity Relationships in Tripodal Transmembrane Anion Transporters: The Effect of Fluorination [J].

Busschaert, Nathalie ;

Wenzel, Marco ;

Light, Mark E. ;

Iglesias-Hernandez, Paulina ;

Perez-Tomas, Ricardo ;

Gale, Philip A. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (35) :14136-14148

[7] A pseudorotaxane umbrella thread with chloride transmembrane transport properties [J].

Chhun, Christine ;

Schmitzer, Andreea R. .

MEDCHEMCOMM, 2011, 2 (10) :987-990

[8] The sonogashira reaction:: A booming methodology in synthetic organic chemistry [J].

Chinchilla, Rafael ;

Najera, Carmen .

CHEMICAL REVIEWS, 2007, 107 (03) :874-922

[9]

Connors K. A., 1987, Binding Constants: The Measurement of Molecular Complex Stability

[10] Development of synthetic membrane transporters for anions [J].

Davis, Anthony P. ;

Sheppard, David N. ;

Smith, Bradley D. .

CHEMICAL SOCIETY REVIEWS, 2007, 36 (02) :348-357

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