Synthesis of New Sulfur-Substituted Pentacyclic 1,2,4-Triazolopyrimidine Derivatives

被引：4

作者：

Sirakanyan, S. N. ^{[1
]}

Hakobyan, E. K. ^{[1
]}

Hovakimyan, A. A. ^{[1
]}

机构：

[1] Natl Acad Sci Armenia, Mndzhoyan Inst Fine Organ Chem, Sci Technol Ctr Organ & Pharmaceut Chem, Pr Azatutyan 26, Yerevan 0014, Armenia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 55卷 / 03期

关键词：

triazolo[4,3-c]pyrimidine; triazolo[1,5-c]pyrimidine; isomerization; Dimroth rearrangement; S-alkylation;

D O I：

10.1134/S1070428019030059

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pentacyclic heterocyclic compounds containing a 1,2,4-triazole ring have been synthesized from [5-(2-methylpropyl)-1,2,3,4-tetrahydropyrimido[4,5: 4,5]thieno[2,3-c]isoquinolin-8-yl]hydrazine. The synthesized [1,2,4]triazolo[4,3-c]pyrimidine derivatives have been found to undergo Dimroth rearrangement in both acidic and basic media.

引用

页码：308 / 313

页数：6

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