Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

被引：52
作者：
Jia, Bei [1 ]
Wang, Liru [1 ,2 ]
Claxton, David F. [1 ]
Ehmann, W. Christopher [1 ]
Rybka, Witold B. [1 ]
Mineishi, Shin [1 ]
Rizvi, Syed [3 ]
Shike, Hiroko [4 ]
Bayerl, Michael [4 ]
Schell, Todd D. [1 ,5 ]
Hohl, Raymond J. [1 ]
Zheng, Hong [1 ]
机构：
[1] Penn State Univ, Coll Med, Penn State Canc Inst, Hershey, PA 17033 USA
[2] Capital Med Univ, Fu Xing Hosp, Beijing 100038, Peoples R China
[3] UT Southwestern Med Ctr, Div Hematol Oncol, Dept Med, Dallas, TX 75390 USA
[4] Penn State Univ, Coll Med, Dept Pathol, Hershey, PA 17033 USA
[5] Penn State Univ, Coll Med, Dept Microbiol & Immunol, Hershey, PA 17033 USA
来源：
BLOOD CANCER JOURNAL | 2018年 / 8卷
关键词：
EXHAUSTION; CANCER;
D O I：
10.1038/s41408-018-0069-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：5
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