CT Perfusion in Oncologic Imaging: A Useful Tool?

被引：133
作者：
Garcia-Figueiras, Roberto [1 ]
Goh, Vicky J. [2 ]
Padhani, Anwar R. [3 ]
Baleato-Gonzalez, Sandra [1 ]
Garrido, Miguel [4 ]
Leon, Luis [5 ]
Gomez-Caamano, Antonio [6 ]
机构：
[1] Univ Santiago de Compostela, Complexo Hosp, Dept Radiol, Santiago De Compostela 15702, Spain
[2] Kings Coll London, Dept Clin Canc Imaging, Div Imaging Sci & Biomed Engn, London WC2R 2LS, England
[3] Mt Vernon Canc Ctr, Paul Strickland Scanner Ctr, Northwood, Middx, England
[4] Univ Santiago de Compostela, Complexo Hosp, Dept Nucl Med, Santiago De Compostela 15702, Spain
[5] Univ Santiago de Compostela, Complexo Hosp, Dept Med Oncol, Santiago De Compostela 15702, Spain
[6] Univ Santiago de Compostela, Complexo Hosp, Dept Radiotherapy, Santiago De Compostela 15702, Spain
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2013年 / 200卷 / 01期
关键词：
angiogenesis; oncology; perfusion CT; COMPUTED-TOMOGRAPHY PERFUSION; CELL LUNG-CANCER; TUMOR BLOOD-FLOW; MULTIDETECTOR-ROW CT; COLORECTAL-CANCER; QUANTITATIVE ASSESSMENT; VASCULAR PARAMETERS; HEPATOCELLULAR-CARCINOMA; ANTIANGIOGENIC THERAPY; TREATMENT RESPONSE;
D O I：
10.2214/AJR.11.8476
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. This article summarizes the current status of CT perfusion in oncologic imaging, including lesion characterization, staging, prediction of patient outcome or response to therapy, assessment of response to different therapies, and evaluation of tumor relapse. Technical limitations and drawbacks of CT perfusion are also discussed. CONCLUSION. Tumor angiogenesis is essential for cancer growth and provides an attractive target for oncologic therapies. CT perfusion is an emerging imaging tool that provides both qualitative and quantitative information regarding tumor angiogenesis.
引用
收藏
页码：8 / 19
页数：12
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