Evolutionary genetics of Trypanosoma and Leishmania

被引：45

作者：

Tibayrenc, M

Ayala, FJ

机构：

[1] CEPM, UMR, CNRS, IRD 9926, F-34032 Rennes, France

[2] Univ Calif Irvine, Dept Ecol & Evolutionary Biol, Irvine, CA 92697 USA

来源：

MICROBES AND INFECTION | 1999年 / 1卷 / 06期

关键词：

molecular epidemiology; population genetics; clonality; linkage disequilibrium; Chagas' disease; pathogenesis;

D O I：

10.1016/S1286-4579(99)80050-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We review recent advances in the study of population structure and phylogenetic diversity of parasites belonging to the genera Trypanosoma and Leishmania. In all species properly analyzed, these parasites exhibit a basically clonal population structure, with occasional bouts of genetic exchange or hybridization, and a strong structuration of their populations into discrete evolutionary lineages. On an evolutionary scale, the impact of sex appears to be greater in African than in American trypanosomes. The taxonomic status of some Leishmania 'species' is questionable. (C) Elsevier, Paris.

引用

页码：465 / 472

页数：8

共 53 条

[1] Is sex better? Parasites say "no" [J].