New light on p27kip1 in breast cancer

被引：20

作者：

Belletti, Barbara ^{[1
]}

Baldassarre, Gustavo ^{[1
]}

机构：

[1] IRCCS, Natl Canc Inst, Ctr Riferimento Oncol, Div Expt Oncol 2, Aviano, Italy

来源：

CELL CYCLE | 2012年 / 11卷 / 19期

关键词：

CELL MOTILITY; INHIBITOR P27; INVASION; CYCLE;

D O I：

10.4161/cc.21573

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：3701 / 3702

页数：2

共 12 条

[1] p27Kip1-stathmin interaction influences sarcoma cell migration and invasion [J].

Baldassarre, G ;

Belletti, B ;

Nicoloso, MS ;

Schiappacassi, M ;

Vecchione, A ;

Spessotto, P ;

Morrione, A ;

Canzonieri, V ;

Colombatti, A .

CANCER CELL, 2005, 7 (01) :51-63

[2] p27kip1 functional regulation in human cancer:: A potential target for therapeutic designs [J].

Belletti, B ;

Nicoloso, MS ;

Schiappacassi, M ;

Chimienti, E ;

Berton, S ;

Lovat, F ;

Colombatti, A ;

Baldassarre, G .

CURRENT MEDICINAL CHEMISTRY, 2005, 12 (14) :1589-1605

[3] The Tumor Suppressor Functions of p27kip1 Include Control of the Mesenchymal/Amoeboid Transition [J].

Berton, Stefania ;

Belletti, Barbara ;

Wolf, Katarina ;

Canzonieri, Vincenzo ;

Lovat, Francesca ;

Vecchione, Andrea ;

Colombatti, Alfonso ;

Friedl, Peter ;

Baldassarre, Gustavo .

MOLECULAR AND CELLULAR BIOLOGY, 2009, 29 (18) :5031-5045

[4] Decreased levels of the cell-cycle inhibitor p27(Kip1) protein: Prognostic implications in primary breast cancer [J].

Catzavelos, C ;

Bhatacharya, N ;

Ung, YC ;

Wilson, JA ;

Roncari, L ;

Sandhu, C ;

Shaw, P ;

Yeger, H ;

MoravaProtzner, I ;

Kapusta, L ;

Franssen, E ;

Pritchard, KI ;

Slingerland, JM .

NATURE MEDICINE, 1997, 3 (02) :227-230

[5] The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy [J].

Chu, Isabel M. ;

Hengst, Ludger ;

Slingerland, Joyce M. .

NATURE REVIEWS CANCER, 2008, 8 (04) :253-267

[6] The murine gene p27Kip1 is haplo-insufficient for tumour suppression [J].

Fero, ML ;

Randel, E ;

Gurley, KE ;

Roberts, JM ;

Kemp, CJ .

NATURE, 1998, 396 (6707) :177-180

[7] p27 as Jekyll and Hyde Regulation of cell cycle and cell motility [J].

Larrea, Michelle D. ;

Wander, Seth A. ;

Slingerland, Joyce M. .

CELL CYCLE, 2009, 8 (21) :3455-3461

[8] RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility [J].

Larreaa, Michelle D. ;

Hong, Feng ;

Wander, Seth A. ;

da Silva, Thiago G. ;

Helfman, David ;

Lannigan, Deborah ;

Smith, Jeffrey A. ;

Slingerland, Joyce M. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (23) :9268-9273

[9] Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas [J].

Loda, M ;

Cukor, B ;

Tam, SW ;

Lavin, P ;

Fiorentino, M ;

Draetta, GF ;

Jessup, JM ;

Pagano, M .

NATURE MEDICINE, 1997, 3 (02) :231-234

[10] p27Kip1 expression inhibits glioblastoma growth, invasion, and tumor-induced neoangiogenesis [J].

Schiappacassi, Monica ;

Lovat, Francesca ;

Canzonieri, Vincenzo ;

Belletti, Barbara ;

Berton, Stefania ;

Di Stefano, Domenica ;

Vecchione, Andrea ;

Colombatti, Alfonso ;

Baldassarre, Gustavo .

MOLECULAR CANCER THERAPEUTICS, 2008, 7 (05) :1164-1175

← 1 2 →