CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences

被引：130

作者：

Ponger, L ^{[1
]}

Mouchiroud, D ^{[1
]}

机构：

[1] Univ Lyon 1, Lab Biometrie & Biol Evolut, CNRS, UMR 5558, F-69622 Villeurbanne, France

来源：

BIOINFORMATICS | 2002年 / 18卷 / 04期

关键词：

D O I：

10.1093/bioinformatics/18.4.631

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Results: CpGProD is an application for identifying mammalian promoter regions associated with CpG islands in large genomic sequences. Although it is strictly dedicated to this particular promoter class corresponding to; approximate to50% of the genes, CpGProD exhibits a higher sensitivity and specificity than other tools used for promoter prediction. Notably, CpGProD uses different parameters according to species (human, mouse) studied. Moreover, CpGProD predicts the promoter orientation on the DNA strand. Availability: http:pbil.univ-lyon1.fr/software/cpgprod.html Supplementary information: http://pbil.univ-lyonl.fr/software/cpgprod.html Contact: ponger@biomserv.univ-lyon1.fr.

引用

页码：631 / 633

页数：3

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