Effect of Ixora coccinea flowers on dead space wound healing in rats

被引:29
作者
Nayak, BS
Udupa, AL
Udupa, SL [1 ]
机构
[1] Kasturba Med Coll, Dept Biochem, Manipal 576119, Karnataka, India
[2] Kasturba Med Coll, Dept Clin Biochem, Manipal 576119, Karnataka, India
[3] Kasturba Med Coll, Dept Pharmacol, Manipal 576119, Karnataka, India
关键词
Ixora coccinea; wound healing activity;
D O I
10.1016/S0367-326X(99)00025-8
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The alcoholic extract of the flowers of Ixora coccinea was studied for its effect on wound healing, using a dead space wound model in rats. Significant increases in granuloma tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content were observed. The prohealing actions seem to be due to increased collagen deposition as well as better alignment and maturation. The drug induced a hypertropic effect on the thymus gland but had no effect on the adrenals. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:233 / 236
页数:4
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