Responsive polymers in controlled drug delivery

被引：1083
作者：
Bajpai, A. K. [1 ]
Shukla, Sandeep K. [1 ]
Bhanu, Smitha [1 ]
Kankane, Sanjana [1 ]
机构：
[1] Govt Autonomous Sci Coll, Dept Chem, Bose Mem Res Lab, Jabalpur 482001, MP, India
来源：
PROGRESS IN POLYMER SCIENCE | 2008年 / 33卷 / 11期
关键词：
Responsive polymers; Hydrogels; Drug delivery;
D O I：
10.1016/j.progpolymsci.2008.07.005
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
This article reviews the state-of-the art in responsive polymer systems for controlled drug delivery applications. The paper describes different types of stimuli-sensitive systems and gives an account of their synthesis through methods such as group transfer polymerization, atom transfer radical polymerization and reversible addition-fragmentation chain transfer polymerization. The article also discusses classification of various drug delivery systems: diffusion controlled systems, chemically controlled systems, swelling-controlled systems and modulated release systems. A survey of the recent literature on various stimuli-responsive polymer hydrogels in controlled drug delivery is also included. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1088 / 1118
页数：31
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