Sclerosing angiomatoid nodular transformation of the spleen

被引:8
作者
Mlik, Olfa Chouchane [1 ]
Lardenois, Segolene [2 ]
Salmon, Remy [2 ]
Servois, Vincent [3 ]
Sastre-Garau, Xavier [1 ]
机构
[1] Inst Curie, Dept Pathol, F-75248 Paris 05, France
[2] Inst Curie, Dept Chirurg, F-75248 Paris 05, France
[3] Inst Curie, Dept Imagerie Med, F-75248 Paris 05, France
关键词
Sclerosing angiomatoid nodular transformation; Spleen; Immunochemistry;
D O I
10.1016/j.annpat.2008.03.006
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a complex vascular lesion recently described. We present a case of SANT occurring in a 49-year-old woman who was treated for choroid melanoma. The computed tomography abdominal scan revealed an asymptomatic mass in the spleen. Splenectomy was performed due to the risk of metastasis from the melanoma. The histopathologic examination revealed an angiomatoid lesion composed of three types of vessels recapitulating the normal composition of the red pulp of the spleen. In this report, we discuss the pathology of this lesion and the differential diagnosis of SANT with other lesions such as hemangiomas, hamartomas and inflammatory pseudotumors. (C) 2008 Elsevier Masson SAS. Taus droits reserves.
引用
收藏
页码:317 / 320
页数:4
相关论文
共 11 条
[1]   Splenic vascular tumors: A histologic, immunophenotypic, and virologic study [J].
Arber, DA ;
Strickler, JG ;
Chen, YY ;
Weiss, LM .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1997, 21 (07) :827-835
[2]  
BUDKE HL, 1995, ARCH PATHOL LAB MED, V119, P755
[3]   NODULAR TRANSFORMATION OF SPLENIC RED PULP DUE TO CARCINOMATOUS INFILTRATION - A DIAGNOSTIC PITFALL [J].
FAKAN, F ;
MICHAL, M .
HISTOPATHOLOGY, 1994, 25 (02) :175-178
[4]   LITTORAL CELL ANGIOMA - A NOVEL SPLENIC VASCULAR LESION DEMONSTRATING HISTIOCYTIC DIFFERENTIATION [J].
FALK, S ;
STUTTE, HJ ;
FRIZZERA, G .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1991, 15 (11) :1023-1033
[5]   Two splenic lesions in need of clarification: Hamartoma and inflammatory pseudotumor [J].
Krishnan, J ;
Frizzera, G .
SEMINARS IN DIAGNOSTIC PATHOLOGY, 2003, 20 (02) :94-104
[6]   Splenic vascular tumors [J].
Kutok, JL ;
Fletcher, CDM .
SEMINARS IN DIAGNOSTIC PATHOLOGY, 2003, 20 (02) :128-139
[7]   Coexisting sclerosing angiomatoid nodular transformation of the spleen with multiple calcifying fibrous pseudotumors in a patient [J].
Lee, Jen-Chieh ;
Lien, Huang-Chun ;
Hsiao, Cheng-Hsiang .
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, 2007, 106 (03) :234-239
[8]   Sclerosing angiomatoid nodular transformation (SANT) of the spleen: Addition of a case with focal CD68 staining and distinctive CT features [J].
Li, L ;
Fisher, DA ;
Stanek, AE .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2005, 29 (06) :839-841
[9]   Sclerosing angiomatoid nodular transformation (SANT) - Report of 25 cases of a distinctive benign splenic lesion [J].
Martel, M ;
Cheuk, W ;
Lombardi, L ;
Lifschitz-Mercer, B ;
Chan, JKC ;
Rosai, J .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2004, 28 (10) :1268-1279
[10]   Isolated diffuse hemangiomatosis of the spleen. Case report and review of literature [J].
Steininger, H ;
Pfofe, D ;
Marquardt, L ;
Sauer, H ;
Markwat, R .
PATHOLOGY RESEARCH AND PRACTICE, 2004, 200 (06) :479-485