Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation

被引:873
作者
Halpin, Stephen J. [1 ,2 ,3 ]
McIvor, Claire [4 ]
Whyatt, Gemma [2 ]
Adams, Anastasia [2 ]
Harvey, Olivia [2 ]
McLean, Lyndsay [5 ]
Walshaw, Christopher [5 ]
Kemp, Steven [6 ]
Corrado, Joanna [2 ]
Singh, Rajinder [2 ]
Collins, Tamsin [3 ]
O'Connor, Rory J. [1 ,2 ]
Sivan, Manoj [1 ,2 ,3 ]
机构
[1] Univ Leeds, Acad Dept Rehabil Med, Leeds Inst Rheumat & Musculoskeletal Med, Sch Med, Leeds, W Yorkshire, England
[2] Leeds Teaching Hosp NHS Trust, Natl Demonstrat Ctr Rehabil Med, Leeds, W Yorkshire, England
[3] Leeds Community Healthcare NHS Trust, Leeds, W Yorkshire, England
[4] Leeds Teaching Hosp NHS Trust, Dept Physiotherapy, Leeds, W Yorkshire, England
[5] Leeds Teaching Hosp NHS Trust, Dept Occupat Therapy, Leeds, W Yorkshire, England
[6] Leeds Beckett Univ, Sch Psychol, Leeds, W Yorkshire, England
关键词
acute respiratory distress syndrome; post-COVID syndrome; post-intensive care syndrome; SARS CoV-2; PULMONARY-FUNCTION; CAPACITY; OUTCOMES; CARE;
D O I
10.1002/jmv.26368
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Background There is currently very limited information on the nature and prevalence of post-COVID-19 symptoms after hospital discharge. Methods A purposive sample of 100 survivors discharged from a large University hospital were assessed 4 to 8 weeks after discharge by a multidisciplinary team of rehabilitation professionals using a specialist telephone screening tool designed to capture symptoms and impact on daily life. EQ-5D-5L telephone version was also completed. Results Participants were between 29 and 71 days (mean 48 days) postdischarge from hospital. Thirty-two participants required treatment in intensive care unit (ICU group) and 68 were managed in hospital wards without needing ICU care (ward group). New illness-related fatigue was the most common reported symptom by 72% participants in ICU group and 60.3% in ward group. The next most common symptoms were breathlessness (65.6% in ICU group and 42.6% in ward group) and psychological distress (46.9% in ICU group and 23.5% in ward group). There was a clinically significant drop in EQ5D in 68.8% in ICU group and in 45.6% in ward group. Conclusions This is the first study from the United Kingdom reporting on postdischarge symptoms. We recommend planning rehabilitation services to manage these symptoms appropriately and maximize the functional return of COVID-19 survivors.
引用
收藏
页码:1013 / 1022
页数:10
相关论文
共 24 条
[11]   Return to work after critical illness: a systematic review and meta-analysis [J].
Kamdar, Biren B. ;
Suri, Rajat ;
Suchyta, Mary R. ;
Digrande, Kyle F. ;
Sherwood, Kyla D. ;
Colantuoni, Elizabeth ;
Dinglas, Victor D. ;
Needham, Dale M. ;
Hopkins, Ramona O. .
THORAX, 2020, 75 (01) :17-27
[12]   The EQ-5D-5L health status questionnaire in COPD: validity, responsiveness and minimum important difference [J].
Nolan, Claire M. ;
Longworth, Louise ;
Lord, Joanne ;
Canavan, Jane L. ;
Jones, Sarah E. ;
Kon, Samantha S. C. ;
Man, William D-C .
THORAX, 2016, 71 (06) :493-500
[13]   Pulmonary function and exercise capacity in survivors of severe acute respiratory syndrome [J].
Ong, KC ;
Ng, AWK ;
Lee, LSU ;
Kaw, G ;
Kwek, SK ;
Leow, MS ;
Earnest, A .
EUROPEAN RESPIRATORY JOURNAL, 2004, 24 (03) :436-442
[14]  
Pan T, 2020, SCAND J GASTROENTERO, V55, P123, DOI [10.1080/00365521.2019.1707275, 10.14309/ajg.0000000000000620]
[15]  
Sivan M, 2020, Adv Clin Neurosciences Rehabil, V19, P14, DOI [10.47795/NELE5960, DOI 10.47795/NELE5960]
[16]   COVID-19 AND POST INTENSIVE CARE SYNDROME: A CALL FOR ACTION [J].
Stam, Henk J. ;
Stucki, Gerold ;
Bickenbach, Jerome .
JOURNAL OF REHABILITATION MEDICINE, 2020, 52 (04)
[17]   One-year outcomes and health care utilization in survivors of severe acute respiratory syndrome [J].
Tansey, Catherine M. ;
Louie, Marie ;
Loeb, Mark ;
Gold, Wayne L. ;
Muller, Matthew P. ;
de Jager, JoAnne ;
Cameron, Jill I. ;
Tomlinson, George ;
Mazzulli, Tony ;
Walmsley, Sharon L. ;
Rachlis, Anita R. ;
Mederski, Barbara D. ;
Silverman, Mike ;
Shainhouse, Zev ;
Ephtimios, Issa E. ;
Avendano, Monica ;
Downey, James ;
Styra, Rima ;
Yamamura, Deborah ;
Gerson, Marvin ;
Stanbrook, Matthew B. ;
Marras, Theodore K. ;
Phillips, Elizabeth J. ;
Zamel, Noe ;
Richardson, Susan E. ;
Slutsky, Arthur S. ;
Herridge, Margaret S. .
ARCHIVES OF INTERNAL MEDICINE, 2007, 167 (12) :1312-1320
[18]  
Wade D, 2013, MINERVA ANESTESIOL, V79, P944
[19]   Clinical features and outcomes of discharged coronavirus disease 2019 patients: a prospective cohort study [J].
Wang, X. ;
Xu, H. ;
Jiang, H. ;
Wang, L. ;
Lu, C. ;
Wei, X. ;
Liu, J. ;
Xu, S. .
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2020, 113 (09) :657-665
[20]   A longitudinal modelling study estimates acute symptoms of community acquired pneumonia recover to baseline by 10 days [J].
Wootton, Daniel G. ;
Dickinson, Laura ;
Pertinez, Henry ;
Court, Joanne ;
Eneje, Odiri ;
Keogan, Lynne ;
Macfarlane, Laura ;
Wilks, Sarah ;
Gallagher, Jane ;
Woodhead, Mark ;
Gordon, Stephen B. ;
Diggle, Peter J. .
EUROPEAN RESPIRATORY JOURNAL, 2017, 49 (06)