The human milk microbiome and factors influencing its composition and activity

被引：172

作者：

Gomez-Gallego, Carlos ^{[1
]}

Garcia-Mantrana, Izaskun ^{[2
]}

Salminen, Seppo ^{[1
]}

Carmen Collado, Maria ^{[1
,2
]}

机构：

[1] Univ Turku, Funct Foods Forum, Fac Med, Turku, Finland

[2] IATA CSIC, Natl Res Council, Inst Agrochem & Food Technol, Dept Biotechnol, Valencia, Spain

来源：

SEMINARS IN FETAL & NEONATAL MEDICINE | 2016年 / 21卷 / 06期

基金：

欧洲研究理事会;

关键词：

Milk microbiota; Lactation; Cesarean section; Diet; Gestational age; LACTIC-ACID BACTERIA; HUMAN BREAST-MILK; GUT MICROBIOTA; PROBIOTIC SUPPLEMENTATION; INTESTINAL MICROBIOTA; MATERNAL WEIGHT; LATE PREGNANCY; IMMUNE-SYSTEM; INFANT; IMPACT;

D O I：

10.1016/j.siny.2016.05.003

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Beyond its nutritional aspects, human milk contains several bioactive compounds, such as microbes, oligosaccharides, and other substances, which are involved in host microbe interactions and have a key role in infant health. New techniques have increased our understanding of milk microbiota composition, but few data on the activity of bioactive compounds and their biological role in infants are available. Whereas the human milk microbiome may be influenced by specific factors including genetics, maternal health and nutrition, mode of delivery, breastfeeding, lactation stage, and geographic location the impact of these factors on the infant microbiome is not yet known. This article gives an overview of milk microbiota composition and activity, including factors influencing microbial composition and their potential biological relevance on infants' future health. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：400 / 405

页数：6

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