Current Use of Probiotics and Prebiotics in Allergy

被引：44
作者：
Fiocchi, Alessandro [1 ]
Cabana, Michael D. [2 ,3 ]
Mennini, Maurizio [1 ]
机构：
[1] IRCCS, Allergy Unit, Bambino Gesu Childrens Hosp, Translat Res Pediat Special Area, Rome, Italy
[2] Albert Einstein Coll Med, Dept Pediat, Bronx, NY 10467 USA
[3] Childrens Hosp Montefiore, Bronx, NY USA
来源：
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE | 2022年 / 10卷 / 09期
关键词：
Food allergy; Asthma; Allergic rhinitis; Atopic dermatitis; Probiotics; Prebiotics; ACID-BASED FORMULA; COWS MILK ALLERGY; INTERNATIONAL SCIENTIFIC ASSOCIATION; HYDROLYZED CASEIN FORMULA; PLACEBO-CONTROLLED TRIAL; RISK ASIAN INFANTS; 1ST; MONTHS; DOUBLE-BLIND; ATOPIC-DERMATITIS; PRIMARY PREVENTION;
D O I：
10.1016/j.jaip.2022.06.038
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
The microbiome plays an important role in the pathogenesis of allergic diseases. This review updates the reader on studies aimed at influencing allergic diseases through modulation of the gut microflora. A nonsystematic review of the literature was performed, focusing on relevant trials evaluating the effect of probiotics/prebiotics/symbiotics in the prevention and treatment of allergic disease. For each allergic disease, we were able to find not only a substantial number of clinical trials but also systematic reviews. Specific guidelines, based on systematic reviews and meta-analyses, are available for the prevention of allergic disease and for the treatment of food allergy. In each of the areas examined-allergic rhinitis, allergic asthma, atopic dermatitis, food allergy, and gastrointestinal allergies-there are substantial uncertainties in the efficacy of gut microflora modulation in prevention and treatment. At present, practicing clinicians can avail themselves of intestinal flora modulators as an adjunct in the prevention of atopic dermatitis but not of other forms of allergic diseases. Their effects on the treatment of allergic diseases remain controversial. (C) 2022 American Academy of Allergy, Asthma & Immunology
引用
收藏
页码：2219 / 2242
页数：24
相关论文
共 156 条
[1]   Probiotics in prevention of IgE-associated eczema:: A double-blind, randomized, placebo-controlled trial [J].
Abrahamsson, Thomas R. ;
Jakobsson, Ted ;
Bottcher, Malin Fageras ;
Fredrikson, Mats ;
Jenmalm, Maria C. ;
Bjorksten, Bengt ;
Oldaeus, Goran .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (05) :1174-1180
[2]   No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy [J].
Abrahamsson, Thomas R. ;
Jakobsson, Ted ;
Bjorksten, Bengt ;
Oldaeus, Goran ;
Jenmalm, Maria C. .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2013, 24 (06) :556-561
[3]   Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis [J].
Alexander, Eileen S. ;
Martin, Lisa J. ;
Collins, Margaret H. ;
Kottyan, Leah C. ;
Sucharew, Heidi ;
He, Hua ;
Mukkada, Vincent A. ;
Succop, Paul A. ;
Abonia, J. Pablo ;
Foote, Heather ;
Eby, Michael D. ;
Grotjan, Tommie M. ;
Greenler, Alexandria J. ;
Dellon, Evan S. ;
Demain, Jeffrey G. ;
Furuta, Glenn T. ;
Gurian, Larry E. ;
Harley, John B. ;
Hopp, Russell J. ;
Kagalwalla, Amir ;
Kaul, Ajay ;
Nadeau, Kari C. ;
Noel, Richard J. ;
Putnam, Philip E. ;
von Tiehl, Karl F. ;
Rothenberg, Marc E. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (05) :1084-+
[4]   Treatment with a Probiotic Mixture Containing Bifidobacterium animalis Subsp. Lactis BB12 and Enterococcus faecium L3 for the Prevention of Allergic Rhinitis Symptoms in Children: A Randomized Controlled Trial [J].
Anania, Caterina ;
Di Marino, Vincenza Patrizia ;
Olivero, Francesca ;
De Canditiis, Daniela ;
Brindisi, Giulia ;
Iannilli, Federico ;
De Castro, Giovanna ;
Zicari, Anna Maria ;
Duse, Marzia .
NUTRIENTS, 2021, 13 (04)
[5]  
Arslanoglu S, 2012, J Biol Regul Homeost Agents, V26, P49
[6]   Early dietary intervention with a mixture of prebiotic oligosaccharides reduces the incidence of allergic manifestations and infections during the first two years of life [J].
Arslanoglu, Sertac ;
Moro, Guido E. ;
Schmitt, Joachim ;
Tandoi, Laura ;
Rizzardi, Silvia ;
Boehm, Gunther .
JOURNAL OF NUTRITION, 2008, 138 (06) :1091-1095
[7]   Infant gut microbiota and food sensitization: associations in the first year of life [J].
Azad, M. B. ;
Konya, T. ;
Guttman, D. S. ;
Field, C. J. ;
Sears, M. R. ;
HayGlass, K. T. ;
Mandhane, P. J. ;
Turvey, S. E. ;
Subbarao, P. ;
Becker, A. B. ;
Scott, J. A. ;
Kozyrskyj, A. L. .
CLINICAL AND EXPERIMENTAL ALLERGY, 2015, 45 (03) :632-643
[8]   Inflammation-associated microbiota in pediatric eosinophilic esophagitis [J].
Benitez, Alain J. ;
Hoffmann, Christian ;
Muir, Amanda B. ;
Dods, Kara K. ;
Spergel, Jonathan M. ;
Bushman, Frederic D. ;
Wang, Mei-Lun .
MICROBIOME, 2015, 3
[9]   First evaluation of a symbiotic food supplement in an allergen exposure chamber in birch pollen allergic patients [J].
Bergmann, Karl-Christian ;
Krause, Linda ;
Hiller, Julia ;
Becker, Sylvia ;
Kugler, Sebastian ;
Tapparo, Martin ;
Pfaar, Oliver ;
Zuberbier, Torsten ;
Kramer, Matthias F. ;
Guethoff, Sonja ;
Graessel, Anke .
WORLD ALLERGY ORGANIZATION JOURNAL, 2021, 14 (01)
[10]   Tralokinumab in Atopic Dermatitis: A Profile of Its Use [J].
Blair, Hannah A. .
CLINICAL DRUG INVESTIGATION, 2022, 42 (04) :365-374
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