Conjugates of a secoiridoid glucoside with a phenolic glucoside from the flower buds of Lonicera japonica Thunb

被引：37

作者：

Kashiwada, Yoshiki ^{[1
]}

Omichi, Yuka ^{[1
]}

Kurimoto, Shin-ichiro ^{[1
]}

Shibata, Hirofumi ^{[1
]}

Miyake, Yoshiyuki ^{[2
]}

Kirimoto, Tsukasa ^{[2
]}

Takaishi, Yoshihisa ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

[2] Taiho Pharmaceut Co Ltd, Prod Res, SH Prod Strategy Planning, Consumer Healthcare, Tokushima 7710194, Japan

来源：

PHYTOCHEMISTRY | 2013年 / 96卷

关键词：

Lonicera japonica; Caprifoliaceae; Secoiridoid; Nicotonic acid; Eugenol; Anti-influenza; GINGYO-SAN; IN-VITRO; INFLUENZA; GLYCOSIDES; MEDICINE;

D O I：

10.1016/j.phytochem.2013.09.021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Secoiridoid glucosides, including two conjugates with a phenolic and two conjugates with a nicotinic acid derivative (3 and 4), together with seven known secoiridoid derivatives, were isolated from flower buds of Lonicera japonica. The structures were elucidated by spectroscopic analyses. Anti-influenza activities of six isolated compounds were also evaluated by plaque assay and neuraminidase inhibitory assay. (C) 2013 Elsevier Ltd. All rights reserved.

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页码：423 / 429

页数：7

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