Traditional herbal medicine as adjunctive therapy for breast cancer: A systematic review

被引:33
作者
Kim, Woojin [1 ]
Lee, Won-Bock [1 ]
Lee, Jung-Woo [1 ]
Min, Byung-Il [1 ,2 ]
Baek, Sun Kyung [3 ]
Lee, Hyang Sook [4 ]
Cho, Seung-Hun [5 ]
机构
[1] Kyung Hee Univ, Grad Sch, Dept East West Med, Seoul 130701, South Korea
[2] Kyung Hee Univ, Coll Med, Dept Physiol, Seoul 130701, South Korea
[3] Kyung Hee Univ Hosp, Dept Internal Med, Seoul 130701, South Korea
[4] Kyung Hee Univ, Coll Korean Med, Acupuncture & Meridian Sci Res Ctr, Seoul 130701, South Korea
[5] Kyung Hee Univ, Med Ctr, Hosp Korean Med, Seoul 130701, South Korea
基金
新加坡国家研究基金会;
关键词
Breast cancer; Alternative medicine; QOL; Traditional herbal medicine; QUALITY-OF-LIFE; JUZEN-TAIHO-TO; LONG-TERM; IN-VITRO; SURVIVORS;
D O I
10.1016/j.ctim.2015.03.011
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Objectives: To assess the effectiveness of traditional herbal medicine (THM) as adjunctive therapy for breast cancer as evidenced by randomized controlled trials (RCTs). Methods: Five electronic English and Chinese databases were systematically searched up to February, 2014. Alt RCTs involving THM in combination with conventional cancer therapy for breast cancer were included. Results: Eight RCTs involving 798 breast cancer patients were systematically reviewed. Three studies reported a significant difference in the improvement of quality of life (QOL) compared to the control group. Two studies reported an increase in the white blood cell count after treatment. Data on hot flashes and sleep quality were evaluated. However, no significant differences in immediate tumor response were observed. Conclusion: THM combined with conventional therapy in the treatment of breast cancer is efficacious in improving QOL and in decreasing the number of hot flashes per day. More research and well-designed, rigorous, large clinical trials are necessary to further address these issues. (C) 2015 Published by Elsevier Ltd.
引用
收藏
页码:626 / 632
页数:7
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