Synthesis of N,N′-disubstituted (1R,2R)-1,2-diaminocyclohex-4-enes by a ruthenium-catalyzed ring-closing metathesis reaction

被引：0

作者：

Alvaro, G ^{[1
]}

Grilli, S ^{[1
]}

Martelli, G ^{[1
]}

Savoia, D ^{[1
]}

机构：

[1] Univ Bologna, Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 1999卷 / 07期

关键词：

ruthenium; ring-closing metathesis; metathesis; EPC synthesis; 1,2-diaminocyclohex-4-ene;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantiopure (1R,2R)-1,2-diaminocyclohex-4-ene derivatives have been synthesized by the ruthenium-catalyzed ring-closing metathesis reaction of (4R,5R)-N,N'-bis [(S)-1-phenylethyl]-4,5-diamino-1,7-octadiene dihydrochloride.

引用

页码：1523 / 1526

页数：4

共 62 条

[1] Synthesis and X-ray crystal structure of N,N-bis[(S)-1-phenylethyl]-(R,R)-4,5-diamino-1,7-octadiene
Alvaro, G
Grepioni, F
Savoia, D
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (12) : 4180 - 4182
[2] Armstrong SK, 1998, J CHEM SOC PERK T 1, P371
[3] trans-1,2-diaminocyclohexane derivatives as chiral reagents, scaffolds, and ligands for catalysis: Applications in asymmetric synthesis and molecular recognition
Bennani, YL
Hanessian, S
[J]. CHEMICAL REVIEWS, 1997, 97 (08) : 3161 - 3195
[4] USE OF CARBOXYLIC-ACIDS AS CHIRAL SOLVATING AGENTS FOR THE DETERMINATION OF OPTICAL PURITY OF CHIRAL AMINES BY NMR-SPECTROSCOPY
BENSON, SC
CAI, P
COLON, M
HAIZA, MA
TOKLES, M
SNYDER, JK
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (22) : 5335 - 5341
[5] Ring closing metathesis of vinyl glycine derivatives
Campagne, JM
Ghosez, L
[J]. TETRAHEDRON LETTERS, 1998, 39 (34) : 6175 - 6178
[6] Cere V, 1998, SYNLETT, P1197
[7] Enders D, 1996, SYNTHESIS-STUTTGART, P1443
[8] NAPHTHO AND BENZO ANALOGS OF THE KAPPA OPIOID AGONIST TRANS-(+/-)-3,4-DICHLORO-N-METHYL-N-[2-(1-PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE
FREEMAN, JP
MICHALSON, ET
DANDREA, SV
BACZYNSKYJ, L
VONVOIGTLANDER, PF
LAHTI, RA
SMITH, MW
LAWSON, CF
SCAHILL, TA
MIZSAK, SA
SZMUSZKOVICZ, J
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (06) : 1891 - 1896
[9] CATALYTIC RING-CLOSING METATHESIS OF FUNCTIONALIZED DIENES BY A RUTHENIUM CARBENE COMPLEX
FU, GC
NGUYEN, ST
GRUBBS, RH
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (21) : 9856 - 9857
[10] Macrocycles by ring-closing metathesis
Furstner, A
Langemann, K
[J]. SYNTHESIS-STUTTGART, 1997, (07): : 792 - &

← 1 2 3 4 5 6 7 →