Solubility of mesalazine in polyethylene glycol 400+water mixtures at different temperatures

被引：15

作者：

Moradi, Milad ^{[1
,2
,3
]}

Rahimpour, Elaheh ^{[2
,3
,4
]}

Hemmati, Salar ^{[5
]}

Martinez, Fleming ^{[6
]}

Barzegar-Jalali, Mohammad ^{[3
,7
]}

Jouyban, Abolghasem ^{[2
,3
,8
]}

机构：

[1] Tabriz Univ Med Sci, Fac Pharm, Student Res Comm, Tabriz, Iran

[2] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz, Iran

[3] Tabriz Univ Med Sci, Fac Pharm, Tabriz, Iran

[4] Tabriz Univ Med Sci, Food & Drug Safety Res Ctr, Tabriz, Iran

[5] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran

[6] Univ Nacl Colombia, Fac Ciencias, Dept Farm, Grp Invest Farmaceut Fisicoquim,Sede Bogota, Cra 30 45-03, Bogota, DC, Colombia

[7] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[8] Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran

来源：

JOURNAL OF MOLECULAR LIQUIDS | 2020年 / 314卷

关键词：

Solubility; Mesalazine; Polyethylene glycol 400; Cosolvency models; Dissolution thermodynamics; Preferential solvation; PREFERENTIAL SOLVATION; COSOLVENCY; PREDICTION; MODELS; DRUGS;

D O I：

10.1016/j.molliq.2020.113546

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Temperature-dependent solubility data for mesalazine in the binary system of polyethylene glycol 400 (PEG 400)/water are determined by a shake-flask method at 293.2-313.2 K. The solubility data are validated to five different computational models including the van't Hoff, the mixture response surface, the Yalkowsky, the Jouyban-Acree, and the Jouyban-Acree-van't Hoff. All the investigated models have good correlation and validation according to obtained the mean relative deviations (MRD%) for back-calculated data. Moreover, apparent thermodynamic analysis shows an endothemiic process for mesalazine in (PEG 400 +/- water) mixtures. Further, based on inverse Kirkwood-Buff integrals is observed that mesalazine is preferentially solvated by PEG in all the mixtures. (C) 2020 Elsevier B.V. All rights reserved.

引用

收藏

页数：8

相关论文

共 50 条

[31] Solubility of Pioglitazone Hydrochloride in Binary and Ternary Mixtures of Water, Propylene Glycol, and Polyethylene Glycols 200, 400, and 600 at 298.2 K [J].

Jouyban, Abolghasem ;

Soltanpour, Shahla .

AAPS PHARMSCITECH, 2010, 11 (04) :1713-1717

[32] Thermodynamic analysis of the solubility of triclocarban in ethylene glycol plus water mixtures [J].

Maria Cruz-Gonzalez, Ana ;

Sofia Vargas-Santana, Martha ;

de Jesus Polania-Orozco, Sebastian ;

Patricia Ortiz, Claudia ;

Enrique Cerquera, Nestor ;

Martinez, Fleming ;

Ricardo Delgado, Daniel ;

Jouyban, Abolghasem ;

Acree, William E., Jr. .

JOURNAL OF MOLECULAR LIQUIDS, 2021, 325

[33] Solubility of sildenafil citrate in the binary mixtures of ethylene glycol and water at different temperatures [J].

Hatefi, Ayda ;

Rahimpour, Elaheh ;

Ghafourian, Taravat ;

Martinez, Fleming ;

Barzegar-Jalali, Mohammad ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2020, 299

[34] Solubility of fluphenazine decanoate in aqueous mixtures of polyethylene glycols 400 and 600 at various temperatures [J].

Jouyban, Abolghasem ;

Martinez, Fleming ;

Panahi-Azar, Vahid .

FLUID PHASE EQUILIBRIA, 2014, 368 :58-64

[35] Solubility of Ketoconazole in Polyethylene Glycol 200+Water Mixtures at 298.2-318.2 K [J].

Jouyban, Abolghasem ;

Soleymani, Jafar ;

Soltanpour, Shahla .

JOURNAL OF SOLUTION CHEMISTRY, 2014, 43 (05) :950-958

[36] Solubility of glibenclamide in the aqueous mixtures of polyethylene glycol 400, propylene glycol and N-methyl-pyrrolidone at 298.2 K [J].

Soltanpour, Sh. ;

Jafari, B. ;

Barzegar-Jalali, M. ;

Jouyban, A. .

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2014, 24 (01) :111-115

[37] Solubility of 3-aminosalicylic acid in 2-propanol + water mixtures at different temperatures [J].

Sheikhi-Sovari, Atefeh ;

Rahimpour, Elaheh ;

Martinez, Fleming ;

Hemmati, Salar ;

Zhao, Hongkun ;

Jouyban, Abolghasem .

PHYSICS AND CHEMISTRY OF LIQUIDS, 2022, 60 (01) :68-82

[38] Solubility of sildenafil citrate in propylene glycol plus ethanol mixtures at different temperatures [J].

Rezaei, Homa ;

Rahimpour, Elaheh ;

Martinez, Fleming ;

Zhao, Hongkun ;

Barzegar-Jalali, Mohammad ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2021, 339

[39] Solubility of ketoconazole in the binary mixtures of 2-propanol and water at different temperatures [J].

Zadaliasghar, Samira ;

Jouyban, Abolghasem ;

Martinez, Fleming ;

Barzegar-Jalali, Mohammad ;

Rahimpour, Elaheh .

JOURNAL OF MOLECULAR LIQUIDS, 2020, 300

[40] Solubility and thermodynamic study of mesalazine in propylene glycol+2-propanol mixtures [J].

Poturcu, Kader ;

Zarghampour, Aynaz ;

Rahimpour, Elaheh ;

Hemmati, Salar ;

Zhao, Hongkun ;

Jouyban, Abolghasem .

BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING, 2023, 40 (04) :1227-1238

← 1 2 3 4 5 →