Solubility of mesalazine in polyethylene glycol 400+water mixtures at different temperatures

被引：15

作者：

Moradi, Milad ^{[1
,2
,3
]}

Rahimpour, Elaheh ^{[2
,3
,4
]}

Hemmati, Salar ^{[5
]}

Martinez, Fleming ^{[6
]}

Barzegar-Jalali, Mohammad ^{[3
,7
]}

Jouyban, Abolghasem ^{[2
,3
,8
]}

机构：

[1] Tabriz Univ Med Sci, Fac Pharm, Student Res Comm, Tabriz, Iran

[2] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz, Iran

[3] Tabriz Univ Med Sci, Fac Pharm, Tabriz, Iran

[4] Tabriz Univ Med Sci, Food & Drug Safety Res Ctr, Tabriz, Iran

[5] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran

[6] Univ Nacl Colombia, Fac Ciencias, Dept Farm, Grp Invest Farmaceut Fisicoquim,Sede Bogota, Cra 30 45-03, Bogota, DC, Colombia

[7] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Tabriz, Iran

[8] Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran

来源：

JOURNAL OF MOLECULAR LIQUIDS | 2020年 / 314卷

关键词：

Solubility; Mesalazine; Polyethylene glycol 400; Cosolvency models; Dissolution thermodynamics; Preferential solvation; PREFERENTIAL SOLVATION; COSOLVENCY; PREDICTION; MODELS; DRUGS;

D O I：

10.1016/j.molliq.2020.113546

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Temperature-dependent solubility data for mesalazine in the binary system of polyethylene glycol 400 (PEG 400)/water are determined by a shake-flask method at 293.2-313.2 K. The solubility data are validated to five different computational models including the van't Hoff, the mixture response surface, the Yalkowsky, the Jouyban-Acree, and the Jouyban-Acree-van't Hoff. All the investigated models have good correlation and validation according to obtained the mean relative deviations (MRD%) for back-calculated data. Moreover, apparent thermodynamic analysis shows an endothemiic process for mesalazine in (PEG 400 +/- water) mixtures. Further, based on inverse Kirkwood-Buff integrals is observed that mesalazine is preferentially solvated by PEG in all the mixtures. (C) 2020 Elsevier B.V. All rights reserved.

引用

收藏

页数：8

相关论文

共 50 条

[11] Bosentan solubility in binary mixtures of polyethylene glycol dimethyl ether 250 and water at different temperatures [J].

Jafari, Parisa ;

Rahimpour, Elaheh ;

Jouyban, Abolghasem .

PHYSICS AND CHEMISTRY OF LIQUIDS, 2022, 60 (05) :738-749

[12] Study of Mesalazine Solubility in Ternary Mixtures of Ethanol, Propylene Glycol, and Water at Various Temperatures [J].

Rahimpour, Elaheh ;

Martinez, Fleming ;

Hemmati, Salar ;

Ramezani, Amir M. ;

Jouyban, Abolghasem .

JOURNAL OF PHARMACEUTICAL SCIENCES, 2022, 111 (10) :2758-2764

[13] Prediction of deferiprone solubility in aqueous mixtures of ethylene glycol, propylene glycol and polyethylene glycol 400 at various temperatures [J].

Abbasi, Masoumeh ;

Martinez, Fleming ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2014, 197 :171-175

[14] Solubility study of acetaminophen in the mixtures of acetonitrile and water at different temperatures [J].

Rahimpour, Elaheh ;

Agha, Elnaz Mazaher Haji ;

Martinez, Fleming ;

Barzegar-Jalali, Mohammad ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2021, 324

[15] Solubility study of mesalazine in the aqueous mixtures of a deep-eutectic solvent at different temperatures [J].

Zarghampour, Aynaz ;

Moradi, Milad ;

Martinez, Fleming ;

Hemmati, Salar ;

Rahimpour, Elaheh ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2021, 336

[16] Solubility of Naproxen in Polyethylene Glycol 200+Water Mixtures at Various Temperatures [J].

Panahi-Azar, Vahid ;

Soltanpour, Shahla ;

Martinez, Fleming ;

Jouyban, Abolghasem .

IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2015, 14 (04) :1041-1050

[17] Experimental and computational approaches for measuring minoxidil solubility in propylene glycol plus water mixtures at different temperatures [J].

Pirhayati, Faezeh H. ;

Mirzaeei, Shahla ;

Rahimpour, Elaheh ;

Mohammadi, Ghobad ;

Martinez, Fleming ;

Taghe, Shiva ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2019, 280 :334-340

[18] Solubility and thermodynamic parameters of a novel anti-cancer drug (DHP-5) in polyethylene glycol 400+water mixtures [J].

Shakeel, Faiyaz ;

Bhat, Mashooq A. ;

Haq, Nazrul ;

Fathi-Azarbayjani, Anahita ;

Jouyban, Abolghasem .

JOURNAL OF MOLECULAR LIQUIDS, 2017, 229 :241-245

[19] A laser monitoring technique for determination of mesalazine solubility in propylene glycol and ethanol mixtures at various temperatures [J].

Jouyban-Gharamaleki, Vahid ;

Jouyban, Abolghasem ;

Kuentz, Martin ;

Hemmati, Salar ;

Martinez, Fleming ;

Rahimpour, Elaheh .

JOURNAL OF MOLECULAR LIQUIDS, 2020, 304

[20] Solubility of 3-aminosalicylic acid in 1-propanol + water mixtures at different temperatures [J].

Sheikhi-Sovari, Atefeh ;

Jouyban, Abolghasem ;

Martinez, Fleming ;

Hemmati, Salar ;

Rahimpour, Elaheh .

JOURNAL OF MOLECULAR LIQUIDS, 2021, 325

← 1 2 3 4 5 →