High-risk human papillomaviruses in two different primary tumors in the same patient

被引：2

作者：

de Oliveira Mota, Manlio Tasso ^{[1
]}

Bonilha, Jane Lopes

Rosa, Bruno Miziara ^{[2
]}

Ferraz de Arruda, Jose Germano ^{[2
,3
]}

Soares, Fernando Augusto ^{[4
]}

Vassallo, Jose ^{[5
]}

Calmon, Marilia Freitas ^{[1
]}

Rahal, Paula ^{[1
]}

机构：

[1] Sao Paulo State Univ UNESP, Lab Genom Studies, Dept Biol, BR-15054000 Sao Paulo, Brazil

[2] Sao Jose do Rio Preto FAMERP, Dept Pathol & Legal Med, Sao Paulo, Brazil

[3] Sao Jose do Rio Preto FAMERP, Dept Surg Specialties, Sao Paulo, Brazil

[4] AC Camargo Hosp, Dept Pathol Anat, Sao Paulo, Brazil

[5] Univ Estadual Campinas, Lab Invest & Mol Pathol, CIPED, Sch Med Sci, Campinas, Brazil

来源：

INTERNATIONAL JOURNAL OF UROLOGY | 2013年 / 20卷 / 10期

基金：

巴西圣保罗研究基金会;

关键词：

esophageal cancer; human papillomavirus 16; laryngeal cancer; papillomavirus infections; penile cancer; INFECTION; HPV; CANCERS; LESIONS;

D O I：

10.1111/iju.12096

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Two cases of patients with high-risk human papillomavirus-related squamous cell carcinomas of the penis are reported. In both patients, a second high-risk human papillomavirus-related squamous cell carcinoma, of the same type (genotype 16), was detected: a carcinoma of the oropharynx 2 years after treatment of the squamous cell carcinomas of the penis in the first patient, and a carcinoma of the esophagus 1 year after the treatment of the squamous cell carcinomas of the penis in the second patient. To the best of our knowledge, this is the first time that multiple human papillomavirus-related tumors in the same patient are reported. It is suggested that a careful clinical investigation is necessary in patients with tumors attributable to high-risk human papillomavirus for the early detection of a possible second neoplasm related to this virus in a different organ.

引用

页码：1046 / 1048

页数：3

共 11 条

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