syn-trans fused bicyclic ether formation via acetylene-biscobalthexacarbonyl complex

被引：67

作者：

Isobe, M

Hosokawa, S

Kira, K

机构：

[1] Laboratory of Organic Chemistry, School of Agricultural Sciences, Nagoya University, Chikusa

来源：

CHEMISTRY LETTERS | 1996年 / 06期

关键词：

D O I：

10.1246/cl.1996.473

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Medium size bicyclic ethers of 7-, 8-, and 9-membered rings were synthesized by connection between a hydroxy group on dihydropyranyl ring and a propargylic cation that was stabilized as an acetylene biscobalthexacarbonyl complex under acidic conditions. This cyclization selectively afforded the syn-trans bicyclic ring system often seen in marine toxins such as ciguatoxin.

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页码：473 / 474

页数：2

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