Absolute configuration of halisulfate 3 from the sponge Ircinia sp.

被引：9

作者：

Muller, EL ^{[1
]}

Faulkner, DJ ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,SCRIPPS INST OCEANOG,LA JOLLA,CA 92093

来源：

TETRAHEDRON | 1997年 / 53卷 / 15期

关键词：

D O I：

10.1016/S0040-4020(97)00202-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The absolute configuration of halisulfate 3 (1), a metabolite of the sponge Ircinia sp. from the Philippines, was determined in two steps. The (13S) absolute configuration was derived by application of the chiral amide method using acid 5. The (8R,9S) stereochemistry of the bicyclic ring system was obtained by comparison of the optical rotation of the degradation product 8 with that of an ester 9 of known absolute configuration. (C) 1997 Elsevier Science Ltd.

引用

页码：5373 / 5378

页数：6

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