The relationship between large cavum septum pellucidum and antisocial behavior, callous-unemotional traits and psychopathy in adolescents

被引:27
作者
White, Stuart F. [1 ]
Brislin, Sarah [1 ]
Sinclair, Stephen [1 ]
Fowler, Katherine A. [1 ]
Pope, Kayla [1 ]
Blair, R. James R. [1 ]
机构
[1] NIMH, Unit Affect Cognit Neurosci, NIH, Bethesda, MD 20892 USA
关键词
Conduct disorder; development; FETAL-ALCOHOL-SYNDROME; CONDUCT DISORDER; BRAIN ANOMALIES; CHILDREN; SCHIZOPHRENIA; HYPERACTIVITY; OFFENDERS; AMYGDALA; BOYS; AGGRESSION;
D O I
10.1111/j.1469-7610.2012.02603.x
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Background: The presence of a large cavum septum pellucidum (CSP) has been previously associated with antisocial behavior/psychopathic traits in an adult community sample. Aims: The current study investigated the relationship between a large CSP and symptom severity in disruptive behavior disorders (DBD; conduct disorder and oppositional defiant disorder). Method: Structural MRI scans of youth with DBDs (N=32) and healthy comparison youth (N=27) were examined for the presence of a large CSP and if this was related to symptom severity. Results: Replicating previous results, a large CSP was associated with DBD diagnosis, proactive aggression, and level of psychopathic traits in youth. However, the presence of a large CSP was unrelated to aggression or psychopathic traits within the DBD sample. Conclusions: Early brain mal-development may increase the risk of a DBD diagnosis, but does not mark a particularly severe form of DBD within patients receiving these diagnoses.
引用
收藏
页码:575 / 581
页数:7
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