Gold Nanoparticles Decorated on Carbon Nanotube Modified Screen-printed Electrode for Flow Injection Amperometric Determination of Methyldopa

被引：0
作者：
Upan, Jantima [1 ,2 ]
Themsirimongkon, Suwaphid [1 ,2 ]
Saipanya, Surin [1 ]
Jakmunee, Jaroon [1 ,3 ,4 ]
机构：
[1] Chiang Mai Univ, Fac Sci, Dept Chem, Chiang Mai 50200, Thailand
[2] Chiang Mai Univ, Grad Sch, Chiang Mai 50200, Thailand
[3] Chiang Mai Univ, Fac Sci, Ctr Excellence Innovat Chem, Chiang Mai 50200, Thailand
[4] Chiang Mai Univ, Fac Sci, Res Ctr Chem Dev Hlth Promoting Prod Northern Res, Chiang Mai 50200, Thailand
来源：
CHIANG MAI JOURNAL OF SCIENCE | 2019年 / 46卷 / 03期
关键词：
carbon nanotubes; flow injection analysis; gold nanoparticle; methyldopa; screen printed electrode; SPECTROPHOTOMETRIC DETERMINATION; VOLTAMMETRIC DETERMINATION; SENSITIVE DETERMINATION; PASTE ELECTRODE; SENSOR; FABRICATION; DOPAMINE; LEVODOPA; SYSTEM;
D O I：
暂无
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Gold nanoparticles (AuNPs) decorated on multi-walled carbon nanotubes (MWCNTs) were used as a modifier on the surface of a screen-printed carbon electrode (SPCE) for sensitive determination of methyldopa, which is widely used as an antihypertensive medicine. The electrochemical oxidation of methyldopa on the modified electrode was carried out in flow injection amperometric (FI-amp) system at the applied potential of +400 mV vs Ag/AgCl. As a result, SPCE modified with 20% w/w of gold nanoparticles on carbon nanotube (AuNPs-CNT/SPCE) provided an excellent sensitivity to methyldopa detection. Morphology of AuNPs-CNT was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), and x-ray diffraction (XRD), which indicated a proper distribution of AuNPs on CNT and high electrode areas. Several parameters that affect the response of the modified electrode were studied. The plot of peak height versus methyldopa concentration showed a linear range of 0.2-100 mu M with a detection limit of 0.1 mu M. The proposed flow injection amperometric system was successfully applied for methyldopa determination in real samples.
引用
收藏
页码：537 / 546
页数：10
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