Accurate and rapid estimation of adsorption isotherms in liquid chromatography using the inverse method on plateaus

被引：43

作者：

Arnell, R ^{[1
]}

Forssén, P ^{[1
]}

Fornstedt, T ^{[1
]}

机构：

[1] Univ Uppsala, Dept Surface Biotechnol, BMC, S-75123 Uppsala, Sweden

来源：

JOURNAL OF CHROMATOGRAPHY A | 2005年 / 1099卷 / 1-2期

关键词：

inverse method; numerical method; LC; competitive adsorption isotherms;

D O I：

10.1016/j.chroma.2005.10.043

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The inverse method (IM) is an attractive approach for estimating adsorption isotherm parameters in liquid chromatography (LC), mainly due to its experimental simplicity and low sample consumption. This article presents a new experimental approach, the inverse method on plateaus (IMP), which uses elution profiles on concentration plateaus together with IM. This approach enabled us to obtain very accurate adsorption isotherms that agreed well with those estimated by means of frontal analysis over the entire concentration range under consideration. IMP is recommended when accurate adsorption isotherm estimates are required, and standard IM is insufficient. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：167 / 174

页数：8

共 20 条

[1] Determination of mobile phase effect on single-component adsorption isotherm by use of numerical estimation [J].

Antos, D ;

Piatkowski, W ;

Kaczmarski, K .

JOURNAL OF CHROMATOGRAPHY A, 2000, 874 (01) :1-12

[2]

ARNELL R, UNPUB ANAL CHEM

[3] An interior trust region approach for nonlinear minimization subject to bounds [J].

Coleman, TF ;

Li, YY .

SIAM JOURNAL ON OPTIMIZATION, 1996, 6 (02) :418-445

[4]

Coleman TF., 1994, Mathematical Programming, V67, P189, DOI [DOI 10.1007/BF01582221, 10.1007/BF01582221]

[5] DETERMINATION OF ISOTHERMS FROM CHROMATOGRAPHIC PEAK SHAPES [J].

DOSE, EV ;

JACOBSON, S ;

GUIOCHON, G .

ANALYTICAL CHEMISTRY, 1991, 63 (08) :833-839

[6] Determination of the single component and competitive adsorption isotherms of the 1-indanol enantiomers by the inverse method [J].

Felinger, A ;

Zhou, DM ;

Guiochon, G .

JOURNAL OF CHROMATOGRAPHY A, 2003, 1005 (1-2) :35-49

[7] Numerical determination of the competitive isotherm of enantiomers [J].

Felinger, A ;

Cavazzini, A ;

Guiochon, G .

JOURNAL OF CHROMATOGRAPHY A, 2003, 986 (02) :207-225

[8] Adsorption isotherms of nonionic surfactants in SBA-15 measured by micro-column chromatography [J].

Findenegg, G. H. ;

Eltekov, A. Y. .

JOURNAL OF CHROMATOGRAPHY A, 2007, 1150 (1-2) :236-240

[9] COMPARISON BETWEEN EXPERIMENTAL AND THEORETICAL PROFILES OF HIGH-CONCENTRATION ELUTION BANDS AND LARGE SYSTEM PEAKS IN NONLINEAR CHROMATOGRAPHY [J].

FORNSTEDT, T ;

GUIOCHON, G .

ANALYTICAL CHEMISTRY, 1994, 66 (17) :2686-2693

[10]

FORSSEN P, UNPUB COMPUT CHEM EN

← 1 2 →