Intradermal vaccine delivery: Will new delivery systems transform vaccine administration?

被引:226
作者
Lambert, Paul Henri [1 ]
Laurent, Philippe E. [2 ]
机构
[1] Ctr Vaccinol, CMU, CH-1211 Geneva 4, Switzerland
[2] BD Med Pharmaceut Syst, F-38800 Le Pont De Claix, France
关键词
intradermal injection; ID injection; vaccine delivery;
D O I
10.1016/j.vaccine.2008.03.095
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
There has been a recent resurgence of interest in intradermal vaccine delivery. The physiological advantages of intradermal vaccine delivery have been known for some time, but the difficulties associated with performing an intradermal injection have historically limited its use. New delivery systems currently in development facilitate convenient intradermal vaccination, unlocking the potential advantages of this delivery route, and potentially transforming vaccine delivery. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3197 / 3208
页数:12
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