Neurobiology - Oscillations in the basal ganglia

被引：62

作者：

Wichmann, T ^{[1
]}

DeLong, MR ^{[1
]}

机构：

[1] Emory Univ, Dept Neurol, Atlanta, GA 30322 USA

来源：

NATURE | 1999年 / 400卷 / 6745期

关键词：

D O I：

10.1038/23148

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Neurons within the basal ganglia — a network of brain structures that may influence information processing in the cortex — can fire in oscillatory bursts. A new study sheds light on the origin of these bursts by defining synchronized oscillations in a cell-culture model of the basal ganglia. Interestingly, this 'pacemaker' seems to oscillate at roughly the same frequency as the tremors seen in people with Parkinson's disease.

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页码：621 / 622

页数：2

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