Regulation of the mitochondrial tricarboxylic acid cycle

被引：169

作者：

Nunes-Nesi, Adriano ^{[1
,2
]}

Araujo, Wagner L. ^{[1
]}

Obata, Toshihiro ^{[3
]}

Fernie, Alisdair R. ^{[3
]}

机构：

[1] Univ Fed Vicosa, Dept Biol Vegetal, BR-36570000 Vicosa, MG, Brazil

[2] Univ Fed Vicosa, Max Planck Partner Grp, Dept Biol Vegetal, BR-36570000 Vicosa, MG, Brazil

[3] Max Planck Inst Mol Pflanzenphysiol, D-14476 Potsdam, Germany

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2013年 / 16卷 / 03期

关键词：

DEPENDENT ISOCITRATE DEHYDROGENASE; SUCCINATE-DEHYDROGENASE; NITROGEN ASSIMILATION; TCA CYCLE; PHOTOSYNTHETIC PERFORMANCE; MOLECULAR CHARACTERIZATION; RESPIRATORY METABOLISM; ARABIDOPSIS LEAVES; PLANT-MITOCHONDRIA; ACONITASE ACTIVITY;

D O I：

10.1016/j.pbi.2013.01.004

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Recent years have seen considerable advances in our understanding of the particular physiological roles of the constituent enzymes of the tricarboxylic acid (TCA) cycle. Despite acquiring a fairly comprehensive overview of the functional importance of these proteins relatively little is known concerning how this important pathway is regulated. In this review we concentrate on the mitochondrial reactions since this organelle is the only one in which a full cycle can, at least theoretically, operate. We summarize what is known about the regulation of the enzymes of the pathway both from historical kinetic studies as well as discussing more recent transcriptional and proteomic studies and our enhanced understanding of subcellular compartmentation within the context of metabolic regulation.

引用

页码：335 / 343

页数：9

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