Prevention of Venous Thromboembolism in Hospitalized Patients With Inflammatory Bowel Disease

被引：10

作者：

Chande, Nilesh ^{[1
]}

机构：

[1] Western Univ, Dept Med, Div Gastroenterol, London, ON, Canada

来源：

INFLAMMATORY BOWEL DISEASES | 2013年 / 19卷 / 03期

关键词：

venous thromboembolism; deep vein thrombosis; ulcerative colitis; Crohn's disease; heparin; ACTIVE ULCERATIVE-COLITIS; MOLECULAR-WEIGHT HEPARIN; PLACEBO-CONTROLLED TRIAL; ILL MEDICAL PATIENTS; GUIDELINES; MANAGEMENT; THROMBOSIS; ENOXAPARIN; THERAPY; ADULTS;

D O I：

10.1097/MIB.0b013e31827e7a0f

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Venous thromboembolism is a relatively common and potentially serious complication in inpatients with inflammatory bowel disease (IBD). There are a number of pathophysiologic mechanisms for venous thromboembolism that are specific to patients with IBD that may be active. The use of anticoagulants for prophylaxis against venous thromboembolism in hospitalized patients with IBD needs to be balanced against the potential for worsening of rectal bleeding. Evidence from randomized trials suggests that heparin and low-molecular weight heparin are generally safe to use in patients with active IBD, and a number of guidelines support their use for thromboprophylaxis in this patient population. (Inflamm Bowel Dis 2013;19:669-671)

引用

页码：669 / 671

页数：3

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