Copper-catalyzed intramolecular direct amination of sp2 C-H bonds for the synthesis of N-aryl acridones

被引：79
|
作者：
Zhou, Wang [1 ]
Liu, Yong [2 ]
Yang, Youqing [1 ]
Deng, Guo-Jun [2 ]
机构：
[1] Xiangtan Univ, Coll Chem Engn, Xiangtan 411105, Peoples R China
[2] Xiangtan Univ, Coll Chem, Xiangtan 411105, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 86期
基金：
美国国家科学基金会;
关键词：
OXIDATIVE FUNCTIONALIZATION; SINGLE-ELECTRON; PALLADIUM; AMIDATION; ROUTE; THIOXANTHONES; ACTIVATION; XANTHONES; LACTAMS; AZOLES;
D O I：
10.1039/c2cc35425j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A copper-catalyzed approach for the synthesis of N-aryl acridones via sp(2) C-H bond amination using air as oxidant under neutral conditions is disclosed. This reaction not only provides a complementary method for synthesizing medicinally important acridones, but also offers a new strategy for sp(2) C-H bond amination.
引用
收藏
页码：10678 / 10680
页数：3
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