Mechanisms of action for light therapy: a review of molecular interactions

被引：68
作者：
Prindeze, Nicholas J. [1 ]
Moffatt, Lauren T. [1 ]
Shupp, Jeffrey W. [1 ,2 ]
机构：
[1] MedStar Hlth, MedStar Washington Hosp Ctr, Res Inst, Burn Ctr,Dept Surg, Washington, DC 20010 USA
[2] Catholic Univ Amer, Dept Biomed Engn, Washington, DC 20064 USA
来源：
EXPERIMENTAL BIOLOGY AND MEDICINE | 2012年 / 237卷 / 11期
关键词：
light therapy; mechanism; photobiomodulation; laser therapy; low-level laser therapy; low-level light therapy; CYTOCHROME-C-OXIDASE; LEVEL LASER THERAPY; NITRIC-OXIDE; REACTIVE OXYGEN; POLARIZED-LIGHT; ABSORPTION-MEASUREMENTS; PROMOTES REGENERATION; FUNCTIONAL RECOVERY; CELLULAR-RESPONSES; 3RD-DEGREE BURNS;
D O I：
10.1258/ebm.2012.012180
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Five decades after the first documented use of a laser for wound healing, research in light therapy has yet to elucidate the underlying biochemical pathways causing its effects. The aim of this review is to summarize the current research into the biochemical mechanisms of light therapy in order to better direct future studies. The implication of cytochrome c oxidase as the photoacceptor modulating light therapy is reviewed, as are the predominant hypotheses of the biochemical pathways involved in the stimulation of wound healing, cellular proliferation, production of transcription factors and other reported stimulatory effects.
引用
收藏
页码：1241 / 1248
页数：8
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  • [1] Visible Lasers Were Better Than Invisible Lasers in Accelerating Burn Healing on Diabetic Rats
    Al-Watban, Farouk A. H.
    Zhang, Xing Yang
    Andres, Bernard L.
    Al-Anize, Azizah
    [J]. PHOTOMEDICINE AND LASER SURGERY, 2009, 27 (02) : 269 - 272
  • [2] The electric field induced by light can explain cellular responses to electromagnetic energy: A hypothesis of mechanism
    Amat, A
    Rigau, J
    Waynant, RW
    Ilev, IK
    Anders, JJ
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2006, 82 (02) : 152 - 160
  • [3] Modification of the intrinsic fluorescence and the biochemical behavior of ATP after irradiation with visible and near-infrared laser light
    Amat, A
    Rigau, J
    Waynant, RW
    Ilev, IK
    Tomas, J
    Anders, JJ
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2005, 81 (01) : 26 - 32
  • [4] LOW-POWER LASER IRRADIATION ALTERS THE RATE OF REGENERATION OF THE RAT FACIAL-NERVE
    ANDERS, JJ
    BORKE, RC
    WOOLERY, SK
    VANDEMERWE, WP
    [J]. LASERS IN SURGERY AND MEDICINE, 1993, 13 (01) : 72 - 82
  • [5] Phototherapy promotes regeneration and functional recovery of injured peripheral nerve
    Anders, JJ
    Geuna, S
    Rochkind, S
    [J]. NEUROLOGICAL RESEARCH, 2004, 26 (02) : 233 - 239
  • [6] Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging?
    Annunziato, L
    Parmaccione, A
    Cataldi, M
    Secondo, A
    Castaldo, P
    Di Renzo, G
    Taglialatela, M
    [J]. NEUROBIOLOGY OF AGING, 2002, 23 (05) : 819 - 834
  • [7] Reactive oxygen species: Metabolism, oxidative stress, and signal transduction
    Apel, K
    Hirt, H
    [J]. ANNUAL REVIEW OF PLANT BIOLOGY, 2004, 55 : 373 - 399
  • [8] Low intensity light stimulates nitrite-dependent nitric oxide synthesis but not oxygen consumption by cytochrome c oxidase: Implications for phototherapy
    Ball, Kerri A.
    Castello, Pablo R.
    Poyton, Robert O.
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2011, 102 (03) : 182 - 191
  • [9] Influence of Laser Photobiomodulation on Collagen IV During Skeletal Muscle Tissue Remodeling After Injury in Rats
    Baptista, Juliana
    Martins, Manoela Domingues
    Santos Pavesi, Vanessa Christina
    Bussadori, Sandra Kalil
    Santos Fernandes, Kristianne Porta
    Pinto Junior, Decio dos Santos
    Mesquita Ferrari, Raquel Agnelli
    [J]. PHOTOMEDICINE AND LASER SURGERY, 2011, 29 (01) : 11 - 17
  • [10] Effects of 780-nm Low-Level Laser Therapy with a Pulsed Gallium Aluminum Arsenide Laser on the Healing of a Surgically Induced Open Skin Wound of Rat
    Bayat, Mohammad
    Azari, Afsaneh
    Golmohammadi, Mohammad Ghasem
    [J]. PHOTOMEDICINE AND LASER SURGERY, 2010, 28 (04) : 465 - 470
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