Mechanisms of action for light therapy: a review of molecular interactions

被引：70
作者：
Prindeze, Nicholas J. [1 ]
Moffatt, Lauren T. [1 ]
Shupp, Jeffrey W. [1 ,2 ]
机构：
[1] MedStar Hlth, MedStar Washington Hosp Ctr, Res Inst, Burn Ctr,Dept Surg, Washington, DC 20010 USA
[2] Catholic Univ Amer, Dept Biomed Engn, Washington, DC 20064 USA
来源：
EXPERIMENTAL BIOLOGY AND MEDICINE | 2012年 / 237卷 / 11期
关键词：
light therapy; mechanism; photobiomodulation; laser therapy; low-level laser therapy; low-level light therapy; CYTOCHROME-C-OXIDASE; LEVEL LASER THERAPY; NITRIC-OXIDE; REACTIVE OXYGEN; POLARIZED-LIGHT; ABSORPTION-MEASUREMENTS; PROMOTES REGENERATION; FUNCTIONAL RECOVERY; CELLULAR-RESPONSES; 3RD-DEGREE BURNS;
D O I：
10.1258/ebm.2012.012180
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Five decades after the first documented use of a laser for wound healing, research in light therapy has yet to elucidate the underlying biochemical pathways causing its effects. The aim of this review is to summarize the current research into the biochemical mechanisms of light therapy in order to better direct future studies. The implication of cytochrome c oxidase as the photoacceptor modulating light therapy is reviewed, as are the predominant hypotheses of the biochemical pathways involved in the stimulation of wound healing, cellular proliferation, production of transcription factors and other reported stimulatory effects.
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收藏
页码：1241 / 1248
页数：8
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