Biobanking for Translational Diabetes Research in India

被引:3
作者
Gangadharan, Charitha [1 ]
Wills, Soniya [1 ]
Vangala, Rajani Kanth [2 ]
Sigamani, Alben [1 ]
机构
[1] Narayana Hrudayalaya Fdn, Dept Clin Res, Bangalore, Karnataka, India
[2] Inst Appl Res & Innovat InARI, Bangalore, Karnataka, India
关键词
biological specimen bank; certification; diabetes; ethics and legal issue; India; BIOREPOSITORIES; PROGRESSION; NETWORK; FUTURE;
D O I
10.1089/biores.2019.0052
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
India is declared as the diabetic capital of the world. Clinically well-annotated blood samples will advance diabetes research for better diagnostic and treatment methods. Building a disease-specific biobank with high-quality peripheral blood mononuclear cells (PBMCs) and clinical follow-up data system will serve as a good platform for clinical research in diabetes. Processing and storage of high-quality biospecimen for translational research in diabetes demand the implementation of good clinical laboratory practices. "Certification or accreditation programs" that improve biorepository processes and frameworks are lacking in Indian context. To sustain and translate the research into clinical practice, good governance of the biobank and financial resources is required. For ethical issues related to health needs of the people and participants in the research, issues related to research process, translational research, and commercialization, data sharing should be addressed. For India to be an innovation and sustainable country Indian government is supporting translational research facilities, including biobanks. India has developed biobanks for various diseases; however, diabetes-specific research biorepository is lacking. Given the dangers of diabetic burden, India should set up a diabetes disease-specific repository learning from the global organizations and customize to the needs of Indian context. It is important to have private agencies get involved to develop biobanks and future research as there are commercial goals to translate research into practice. New technologies of specimen storing and preservation, data management, and data sharing should be adopted for developing cost-effective long-standing disease-specific population biobank in India.
引用
收藏
页码:183 / 189
页数:7
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