Programmable Fractal Nanostructured Interfaces for Specific Recognition and Electrochemical Release of Cancer Cells

被引：193

作者：

Zhang, Pengchao ^{[1
,2
]}

Chen, Li ^{[1
,2
]}

Xu, Tailin ^{[1
]}

Liu, Hongliang ^{[1
]}

Liu, Xueli ^{[1
,2
]}

Meng, Jingxin ^{[1
]}

Yang, Gao ^{[1
,2
]}

Jiang, Lei ^{[1
]}

Wang, Shutao ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

ADVANCED MATERIALS | 2013年 / 25卷 / 26期

关键词：

fractal nanostructure; cancer cell recognition; cell release; electrochemistry; CIRCULATING TUMOR-CELLS; SELF-ASSEMBLED MONOLAYERS; EFFICIENT CAPTURE; GOLD CLUSTERS; T-LYMPHOCYTES; SURFACE; DESORPTION; BLOOD; NANOPARTICLES; ARCHITECTURE;

D O I：

10.1002/adma.201300888

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Topographic recognition of cancer cells is triggered by fractal gold nanostructures (FAuNSs), leading to dramatically enhanced recognition capability and efficient release of cancer cells with little damage. The unique characteristic of FAuNSs is the similar fractal dimension of their surface and that of a cancer cell. The design of fractal nanostructures will open up opportunities for functional design of bio-interfaces for highly efficient recognition and release of disease-related rare cells, which will improve detection in a clinical environment. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3566 / 3570

页数：5

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