The Missing Link between Itch and Inflammation in Atopic Dermatitis

被引：21

作者：

Elmariah, Sarina B. ^{[1
,2
]}

Lerner, Ethan A. ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Dept Dermatol, Cutaneous Biol Res Ctr, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Boston, MA 02114 USA

来源：

CELL | 2013年 / 155卷 / 02期

关键词：

THYMIC STROMAL LYMPHOPOIETIN;

D O I：

10.1016/j.cell.2013.09.038

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Atopic dermatitis is a common skin disease with high morbidity and is associated with severe itch and chronic skin inflammation. In this issue of Cell, Wilson et al. demonstrate that epithelial cells communicate directly with cutaneous sensory neurons via a cytokine to induce itch.

引用

页码：267 / 269

页数：3

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