Catalyst-free and atom-economic synthesis of substituted 1-acetyl and 1-hydroxyl carbazoles

被引：5
作者：
Yu, Feng [1 ]
Li, Dan [1 ]
Wei, Yu [1 ]
Kang, Rui-Ming [1 ]
Guo, Qi-Xiang [1 ]
机构：
[1] Southwest Univ, Sch Chem & Chem Engn, Chongqing 400715, Peoples R China
来源：
TETRAHEDRON | 2018年 / 74卷 / 15期
关键词：
3-Alkenyl indole; Diels-Alder; Carbazole; Catalyst-free; Atom-economic; C-H ACTIVATION; FUNCTIONALIZED CARBAZOLES; BIOLOGICAL-ACTIVITIES; INDOLES; DERIVATIVES; ALKALOIDS; CONSTRUCTION; CHEMISTRY; HETEROCYCLES; PERSPECTIVE;
D O I：
10.1016/j.tet.2018.02.066
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first-ever Diels-Alder reactions of 3-alkenyl indoles with a conjugated alkynyl ketone are reported. These reactions proceed in an atom-economic manner without a catalyst and give various substituted 1-acetyl carbazoles in moderate to excellent yields. These products can be converted to 1-hydroxyl carbazoles in high yields under mild reaction conditions. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1965 / 1972
页数：8
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